open access

Vol 19, No 6 (2014)
Original research articles
Published online: 2014-11-01
Submitted: 2014-01-03
Get Citation

Clinical examples of 3D dose distribution reconstruction, based on the actual MLC leaves movement, for dynamic treatment techniques

Wojciech Osewski, Łukasz Dolla, Michał Radwan, Marta Szlag, Roman Rutkowski, Barbara Smolińska, Krzysztof Ślosarek
DOI: 10.1016/j.rpor.2014.04.013
·
Rep Pract Oncol Radiother 2014;19(6):420-427.

open access

Vol 19, No 6 (2014)
Original research articles
Published online: 2014-11-01
Submitted: 2014-01-03

Abstract

Aim

To present practical examples of our new algorithm for reconstruction of 3D dose distribution, based on the actual MLC leaf movement.

Background

DynaLog and RTplan files were used by DDcon software to prepare a new RTplan file for dose distribution reconstruction.

Materials and methods

Four different clinically relevant scenarios were used to assess the feasibility of the proposed new approach: (1) Reconstruction of whole treatment sessions for prostate cancer; (2) Reconstruction of IMRT verification treatment plan; (3) Dose reconstruction in breast cancer; (4) Reconstruction of interrupted arc and complementary plan for an interrupted VMAT treatment session of prostate cancer. The applied reconstruction method was validated by comparing reconstructed and measured fluence maps. For all statistical analysis, the U Mann–Whitney test was used.

Results

In the first two and the fourth cases, there were no statistically significant differences between the planned and reconstructed dose distribution (p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.910, p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.975, p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.893, respectively). In the third case the differences were statistically significant (p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.015). Treatment plan had to be reconstructed.

Conclusion

Developed dose distribution reconstruction algorithm presents a very useful QA tool. It provides means for 3D dose distribution verification in patient volume and allows to evaluate the influence of actual MLC leaf motion on the dose distribution.

Abstract

Aim

To present practical examples of our new algorithm for reconstruction of 3D dose distribution, based on the actual MLC leaf movement.

Background

DynaLog and RTplan files were used by DDcon software to prepare a new RTplan file for dose distribution reconstruction.

Materials and methods

Four different clinically relevant scenarios were used to assess the feasibility of the proposed new approach: (1) Reconstruction of whole treatment sessions for prostate cancer; (2) Reconstruction of IMRT verification treatment plan; (3) Dose reconstruction in breast cancer; (4) Reconstruction of interrupted arc and complementary plan for an interrupted VMAT treatment session of prostate cancer. The applied reconstruction method was validated by comparing reconstructed and measured fluence maps. For all statistical analysis, the U Mann–Whitney test was used.

Results

In the first two and the fourth cases, there were no statistically significant differences between the planned and reconstructed dose distribution (p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.910, p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.975, p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.893, respectively). In the third case the differences were statistically significant (p[[ce:hsp sp="0.25"/]]=[[ce:hsp sp="0.25"/]]0.015). Treatment plan had to be reconstructed.

Conclusion

Developed dose distribution reconstruction algorithm presents a very useful QA tool. It provides means for 3D dose distribution verification in patient volume and allows to evaluate the influence of actual MLC leaf motion on the dose distribution.

Get Citation

Keywords

IMRT; VMAT; DynaLog; RTplan; DICOM

About this article
Title

Clinical examples of 3D dose distribution reconstruction, based on the actual MLC leaves movement, for dynamic treatment techniques

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 19, No 6 (2014)

Pages

420-427

Published online

2014-11-01

DOI

10.1016/j.rpor.2014.04.013

Bibliographic record

Rep Pract Oncol Radiother 2014;19(6):420-427.

Keywords

IMRT
VMAT
DynaLog
RTplan
DICOM

Authors

Wojciech Osewski
Łukasz Dolla
Michał Radwan
Marta Szlag
Roman Rutkowski
Barbara Smolińska
Krzysztof Ślosarek

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk, Poland
tel.:+48 58 320 94 94, fax:+48 58 320 94 60, e-mail: journals@viamedica.pl