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Influence of segment width on plan quality for volumetric modulated arc based stereotactic body radiotherapy
open access
Abstract
Aim
To study the influence of segment width on plan quality for volumetric modulated arc based stereotactic body radiotherapy.
Background
The redundancy of modulation for regularly shaped small volume tumors results in creation of many small segments and an increase of monitor units, with a consequent prolongation of treatment and uncertainty in treatment delivery.
Materials and methods
Six cases each in lung, abdomen and liver were taken for the study. For each case, three VMAT SBRT plans were generated with different penalties on minimum segment width of 0.5, 1.0 and 1.5[[ce:hsp sp="0.25"/]]cm. A comparison was made on the metrics of dose volume histogram, dosimetric indices, monitor units (MUs) and delivery accuracy.
Results
The mean reduction of total MUs when compared with 0.5[[ce:hsp sp="0.25"/]]cm plan was observed as 12.7[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]6.0% and 17.5[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]7.2% for 1.0[[ce:hsp sp="0.25"/]]cm and 1.5[[ce:hsp sp="0.25"/]]cm of minimum segment width, respectively. The p value showed a significant degradation in dosimetric indices for 1.5[[ce:hsp sp="0.25"/]]cm plans when compared with 0.5[[ce:hsp sp="0.25"/]]cm and 1.0[[ce:hsp sp="0.25"/]]cm plans. The average deviation of measured dose with TPS calculated was 3.0[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]1.1%, 2.1[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]0.84% and 1.8[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]0.9% for 0.5, 1.0 and 1.5[[ce:hsp sp="0.25"/]]cm, respectively. The calculated gamma index with pass criteria of 2% dose difference and 2[[ce:hsp sp="0.25"/]]mm distance to agreement was 95.9[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]2.8%, 96.5[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]2.6% and 97.8[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]1.6% as calculated for 0.5, 1.0 and 1.5[[ce:hsp sp="0.25"/]]cm of penalties, respectively. In view of the trade off between delivery efficiency and plan quality, 1[[ce:hsp sp="0.25"/]]cm minimum segment width plans showed an improvement.
Conclusions
VMAT SBRT plans with increased optimal value of minimum segment width showed better plan quality and delivery efficiency for stereotactic body radiotherapy.
Abstract
Aim
To study the influence of segment width on plan quality for volumetric modulated arc based stereotactic body radiotherapy.
Background
The redundancy of modulation for regularly shaped small volume tumors results in creation of many small segments and an increase of monitor units, with a consequent prolongation of treatment and uncertainty in treatment delivery.
Materials and methods
Six cases each in lung, abdomen and liver were taken for the study. For each case, three VMAT SBRT plans were generated with different penalties on minimum segment width of 0.5, 1.0 and 1.5[[ce:hsp sp="0.25"/]]cm. A comparison was made on the metrics of dose volume histogram, dosimetric indices, monitor units (MUs) and delivery accuracy.
Results
The mean reduction of total MUs when compared with 0.5[[ce:hsp sp="0.25"/]]cm plan was observed as 12.7[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]6.0% and 17.5[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]7.2% for 1.0[[ce:hsp sp="0.25"/]]cm and 1.5[[ce:hsp sp="0.25"/]]cm of minimum segment width, respectively. The p value showed a significant degradation in dosimetric indices for 1.5[[ce:hsp sp="0.25"/]]cm plans when compared with 0.5[[ce:hsp sp="0.25"/]]cm and 1.0[[ce:hsp sp="0.25"/]]cm plans. The average deviation of measured dose with TPS calculated was 3.0[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]1.1%, 2.1[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]0.84% and 1.8[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]0.9% for 0.5, 1.0 and 1.5[[ce:hsp sp="0.25"/]]cm, respectively. The calculated gamma index with pass criteria of 2% dose difference and 2[[ce:hsp sp="0.25"/]]mm distance to agreement was 95.9[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]2.8%, 96.5[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]2.6% and 97.8[[ce:hsp sp="0.25"/]]±[[ce:hsp sp="0.25"/]]1.6% as calculated for 0.5, 1.0 and 1.5[[ce:hsp sp="0.25"/]]cm of penalties, respectively. In view of the trade off between delivery efficiency and plan quality, 1[[ce:hsp sp="0.25"/]]cm minimum segment width plans showed an improvement.
Conclusions
VMAT SBRT plans with increased optimal value of minimum segment width showed better plan quality and delivery efficiency for stereotactic body radiotherapy.
Keywords
VMAT SBRT; Optimization; Minimum segment width; Small field measurements


Title
Influence of segment width on plan quality for volumetric modulated arc based stereotactic body radiotherapy
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
287-295
Published online
2014-09-01
DOI
10.1016/j.rpor.2014.03.003
Bibliographic record
Rep Pract Oncol Radiother 2014;19(5):287-295.
Keywords
VMAT SBRT
Optimization
Minimum segment width
Small field measurements
Authors
Karthikeyan Nithiyanantham
Ganesh Kadirampatti Mani
Vikraman Subramani
Karrthick Karukkupalayam Palaniappan
Mohanraj Uthiran
Sennniandavar Vellengiri
Sambasivaselli Raju
Sanjay S. Supe
Tejinder Kataria