open access

Vol 19, No 4 (2014)
Reviews
Published online: 2014-07-01
Submitted: 2013-02-19
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Is stereotactic ablative radiotherapy an alternative to surgery in operable stage I non-small cell lung cancer?

Andrea Riccardo Filippi, Pierfrancesco Franco, Umberto Ricardi
DOI: 10.1016/j.rpor.2013.05.005
·
Rep Pract Oncol Radiother 2014;19(4):275-279.

open access

Vol 19, No 4 (2014)
Reviews
Published online: 2014-07-01
Submitted: 2013-02-19

Abstract

Surgery is the gold therapeutic standard for patients affected with stage I non-small cell lung cancer. Stereotactic ablative radiotherapy is currently considered the preferred treatment option for inoperable patients, representing approximately 25%. Limited data are available directly comparing surgery and SABR in operable patients, none of them prospective. Preliminary results are encouraging, showing that the two treatment modalities are equally effective in terms of tumour control, with expected similar survival projections. Moreover, in elderly patients SABR could represent a valid treatment alternative in comparison to surgery due to the lower morbidity. We here review and discuss the potential role of SABR as an alternative to surgery in operable early stage lung cancer patients.

Abstract

Surgery is the gold therapeutic standard for patients affected with stage I non-small cell lung cancer. Stereotactic ablative radiotherapy is currently considered the preferred treatment option for inoperable patients, representing approximately 25%. Limited data are available directly comparing surgery and SABR in operable patients, none of them prospective. Preliminary results are encouraging, showing that the two treatment modalities are equally effective in terms of tumour control, with expected similar survival projections. Moreover, in elderly patients SABR could represent a valid treatment alternative in comparison to surgery due to the lower morbidity. We here review and discuss the potential role of SABR as an alternative to surgery in operable early stage lung cancer patients.

Get Citation

Keywords

Early stage lung cancer; Stereotactic radiotherapy; Thoracic surgery

About this article
Title

Is stereotactic ablative radiotherapy an alternative to surgery in operable stage I non-small cell lung cancer?

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 19, No 4 (2014)

Pages

275-279

Published online

2014-07-01

DOI

10.1016/j.rpor.2013.05.005

Bibliographic record

Rep Pract Oncol Radiother 2014;19(4):275-279.

Keywords

Early stage lung cancer
Stereotactic radiotherapy
Thoracic surgery

Authors

Andrea Riccardo Filippi
Pierfrancesco Franco
Umberto Ricardi

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