Vol 19, No 4 (2014)
Reviews
Published online: 2014-07-01

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Is stereotactic ablative radiotherapy an alternative to surgery in operable stage I non-small cell lung cancer?

Andrea Riccardo Filippi1, Pierfrancesco Franco2, Umberto Ricardi1
DOI: 10.1016/j.rpor.2013.05.005
Rep Pract Oncol Radiother 2014;19(4):275-279.

Abstract

Surgery is the gold therapeutic standard for patients affected with stage I non-small cell lung cancer. Stereotactic ablative radiotherapy is currently considered the preferred treatment option for inoperable patients, representing approximately 25%. Limited data are available directly comparing surgery and SABR in operable patients, none of them prospective. Preliminary results are encouraging, showing that the two treatment modalities are equally effective in terms of tumour control, with expected similar survival projections. Moreover, in elderly patients SABR could represent a valid treatment alternative in comparison to surgery due to the lower morbidity. We here review and discuss the potential role of SABR as an alternative to surgery in operable early stage lung cancer patients.

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Reports of Practical Oncology and Radiotherapy