open access
Is stereotactic ablative radiotherapy an alternative to surgery in operable stage I non-small cell lung cancer?
open access
Abstract
Surgery is the gold therapeutic standard for patients affected with stage I non-small cell lung cancer. Stereotactic ablative radiotherapy is currently considered the preferred treatment option for inoperable patients, representing approximately 25%. Limited data are available directly comparing surgery and SABR in operable patients, none of them prospective. Preliminary results are encouraging, showing that the two treatment modalities are equally effective in terms of tumour control, with expected similar survival projections. Moreover, in elderly patients SABR could represent a valid treatment alternative in comparison to surgery due to the lower morbidity. We here review and discuss the potential role of SABR as an alternative to surgery in operable early stage lung cancer patients.
Abstract
Surgery is the gold therapeutic standard for patients affected with stage I non-small cell lung cancer. Stereotactic ablative radiotherapy is currently considered the preferred treatment option for inoperable patients, representing approximately 25%. Limited data are available directly comparing surgery and SABR in operable patients, none of them prospective. Preliminary results are encouraging, showing that the two treatment modalities are equally effective in terms of tumour control, with expected similar survival projections. Moreover, in elderly patients SABR could represent a valid treatment alternative in comparison to surgery due to the lower morbidity. We here review and discuss the potential role of SABR as an alternative to surgery in operable early stage lung cancer patients.
Keywords
Early stage lung cancer; Stereotactic radiotherapy; Thoracic surgery
About this articleTitle
Is stereotactic ablative radiotherapy an alternative to surgery in operable stage I non-small cell lung cancer?
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
275-279
Published online
2014-07-01
DOI
10.1016/j.rpor.2013.05.005
Bibliographic record
Rep Pract Oncol Radiother 2014;19(4):275-279.
Keywords
Early stage lung cancer
Stereotactic radiotherapy
Thoracic surgery
Authors
Andrea Riccardo Filippi
Pierfrancesco Franco
Umberto Ricardi