open access

Vol 19, No 2 (2014)
Special Issue Papers
Published online: 2014-03-01
Submitted: 2013-02-28
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Total skin electron beam (TSEB) therapy in pediatric patients: A review of the literature

Małgorzata. Skórska
DOI: 10.1016/j.rpor.2013.06.003
·
Rep Pract Oncol Radiother 2014;19(2):109-113.

open access

Vol 19, No 2 (2014)
Special Issue Papers
Published online: 2014-03-01
Submitted: 2013-02-28

Abstract

Aim

A literature review was undertaken to identify current TSEB therapy in pediatric patients.

Background

Total skin electron beam (TSEB) therapy is a method of irradiation with low energy electron beam dedicated to patients who have superficial skin lesions all over their body. Such skin malignancies are sparse among adults and even more uncommon with pediatric population.

Materials and methods

In this study, all reported case reports were summed up with a special emphasis on techniques used, doses prescribed and special shielding of critical organs. Moreover, potential problems that were encountered during TSEB irradiation of very young patients were depicted.

Results

The literature has described only seven case reports of children undergoing TSEB therapy. Most of them were infants; however, two adolescents were also treated. For all infants, general anesthesia was provided to allow safe and accurate TSEB irradiation. The prescribed dose varied from 16[[ce:hsp sp="0.25"/]]Gy to 28[[ce:hsp sp="0.25"/]]Gy depending on the irradiation schedule and patient condition. Usually, boost fields were applied to the scalp and perineum. Typical shields for fingernails, toenails and lenses were usually used.

Conclusion

This paper revealed that TSEB therapy may be considered as a palliative treatment for pediatric patients with leukemia cutis. However, its role is still unclear and should be further investigated.

Abstract

Aim

A literature review was undertaken to identify current TSEB therapy in pediatric patients.

Background

Total skin electron beam (TSEB) therapy is a method of irradiation with low energy electron beam dedicated to patients who have superficial skin lesions all over their body. Such skin malignancies are sparse among adults and even more uncommon with pediatric population.

Materials and methods

In this study, all reported case reports were summed up with a special emphasis on techniques used, doses prescribed and special shielding of critical organs. Moreover, potential problems that were encountered during TSEB irradiation of very young patients were depicted.

Results

The literature has described only seven case reports of children undergoing TSEB therapy. Most of them were infants; however, two adolescents were also treated. For all infants, general anesthesia was provided to allow safe and accurate TSEB irradiation. The prescribed dose varied from 16[[ce:hsp sp="0.25"/]]Gy to 28[[ce:hsp sp="0.25"/]]Gy depending on the irradiation schedule and patient condition. Usually, boost fields were applied to the scalp and perineum. Typical shields for fingernails, toenails and lenses were usually used.

Conclusion

This paper revealed that TSEB therapy may be considered as a palliative treatment for pediatric patients with leukemia cutis. However, its role is still unclear and should be further investigated.

Get Citation

Keywords

Pediatric total skin electron beam therapy; TSEB; Leukemia cutis

About this article
Title

Total skin electron beam (TSEB) therapy in pediatric patients: A review of the literature

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 19, No 2 (2014)

Pages

109-113

Published online

2014-03-01

DOI

10.1016/j.rpor.2013.06.003

Bibliographic record

Rep Pract Oncol Radiother 2014;19(2):109-113.

Keywords

Pediatric total skin electron beam therapy
TSEB
Leukemia cutis

Authors

Małgorzata. Skórska

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