open access

Vol 18, No 4 (2013)
Original research articles
Published online: 2013-07-01
Submitted: 2012-11-30
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Correlation between clinical findings and magnetic resonance imaging for the assessment of local response after standard treatment in cervical cancer

Izaskun Valduvieco, Albert Biete, Iván Rios, Ricardo Llorente, Angels Rovirosa, Jaume Pahisa, Laura Vidal, Blanca Farrús, Pilar Samper
DOI: 10.1016/j.rpor.2013.04.026
·
Rep Pract Oncol Radiother 2013;18(4):214-219.

open access

Vol 18, No 4 (2013)
Original research articles
Published online: 2013-07-01
Submitted: 2012-11-30

Abstract

Background

The aim of our study is to evaluate the correlation between gynecological examination and magnetic resonance (MRI) findings for the assessment of local response in cervical cancer patients treated with radiotherapy/chemotherapy (RT/ChT).

Patients and methods

This study is a retrospective review of 75 consecutive cervical cancer patients from April 2004 to November 2009 treated with RT/ChT. Clinical and radiological data were subsequently analyzed. Patient's median age was 51 with a FIGO stage from Ib to IVb. Individualized RT/ChT was administered with a median dose of 45[[ce:hsp sp="0.25"/]]Gy. Sixty-three patients received a complementary brachytherapy. Seventy-one patients received chemotherapy on a weekly basis. Gynecological exam was performed 3 months and 6 months after treatment and these findings were compared to MRI results at the same time.

Statistic analysis

We used the Spearman's Rho test to determine the correlation level between the clinical and radiological methods.

Results

A correlation of 0.68 (60%) was observed between the clinical and MRI findings at 3 months with a further increase of up to 0.86 (82.6%) at 6 months. In the few cases with a poor correlation, the subsequent assessment and the natural history of the disease showed a greater value of the clinical exam as compared with the MRI findings.

Conclusions

Physical exam remains an essential tool to evaluate the local response to RT/ChT for cervical cancer. The optimal clinical radiological correlation found at 6 months after treatment suggests that the combination of gynecological examination and MRI are probably adequate in patient monitoring.

Abstract

Background

The aim of our study is to evaluate the correlation between gynecological examination and magnetic resonance (MRI) findings for the assessment of local response in cervical cancer patients treated with radiotherapy/chemotherapy (RT/ChT).

Patients and methods

This study is a retrospective review of 75 consecutive cervical cancer patients from April 2004 to November 2009 treated with RT/ChT. Clinical and radiological data were subsequently analyzed. Patient's median age was 51 with a FIGO stage from Ib to IVb. Individualized RT/ChT was administered with a median dose of 45[[ce:hsp sp="0.25"/]]Gy. Sixty-three patients received a complementary brachytherapy. Seventy-one patients received chemotherapy on a weekly basis. Gynecological exam was performed 3 months and 6 months after treatment and these findings were compared to MRI results at the same time.

Statistic analysis

We used the Spearman's Rho test to determine the correlation level between the clinical and radiological methods.

Results

A correlation of 0.68 (60%) was observed between the clinical and MRI findings at 3 months with a further increase of up to 0.86 (82.6%) at 6 months. In the few cases with a poor correlation, the subsequent assessment and the natural history of the disease showed a greater value of the clinical exam as compared with the MRI findings.

Conclusions

Physical exam remains an essential tool to evaluate the local response to RT/ChT for cervical cancer. The optimal clinical radiological correlation found at 6 months after treatment suggests that the combination of gynecological examination and MRI are probably adequate in patient monitoring.

Get Citation

Keywords

Cervical cancer; Assessment of local response; Correlation clinical/radiological

About this article
Title

Correlation between clinical findings and magnetic resonance imaging for the assessment of local response after standard treatment in cervical cancer

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 18, No 4 (2013)

Pages

214-219

Published online

2013-07-01

DOI

10.1016/j.rpor.2013.04.026

Bibliographic record

Rep Pract Oncol Radiother 2013;18(4):214-219.

Keywords

Cervical cancer
Assessment of local response
Correlation clinical/radiological

Authors

Izaskun Valduvieco
Albert Biete
Iván Rios
Ricardo Llorente
Angels Rovirosa
Jaume Pahisa
Laura Vidal
Blanca Farrús
Pilar Samper

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