open access

Vol 18, No 3 (2013)
Original research articles
Published online: 2013-05-01
Submitted: 2011-07-28
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Measurement verification of dose distributions in pulsed-dose rate brachytherapy in breast cancer

Patrycja Mantaj, Grzegorz Zwierzchowski
DOI: 10.1016/j.rpor.2013.03.001
·
Rep Pract Oncol Radiother 2013;18(3):139-147.

open access

Vol 18, No 3 (2013)
Original research articles
Published online: 2013-05-01
Submitted: 2011-07-28

Abstract

Aim

The aim of the study was to verify the dose distribution optimisation method in pulsed brachytherapy.

Background

The pulsed-dose rate brachytherapy is a very important method of breast tumour treatment using a standard brachytheraphy equipment. The appropriate dose distribution round an implant is an important issue in treatment planning. Advanced computer systems of treatment planning are equipped with algorithms optimising dose distribution.

Materials and methods

The wax-paraffin phantom was constructed and seven applicators were placed within it. Two treatment plans (non-optimised, optimised) were prepared. The reference points were located at a distance of 5[[ce:hsp sp="0.25"/]]mm from the applicators’ axis. Thermoluminescent detectors were placed in the phantom at suitable 35 chosen reference points.

Results

The dosimetry verification was carried out in 35 reference points for the plans before and after optimisation. Percentage difference for the plan without optimisation ranged from −8.5% to 1.4% and after optimisation from −8.3% to 0.01%. In 16 reference points, the calculated percentage difference was negative (from −8.5% to 1.3% for the plan without optimisation and from −8.3% to 0.8% for the optimised plan). In the remaining 19 points percentage difference was from 9.1% to 1.4% for the plan without optimisation and from 7.5% to 0.01% for the optimised plan.

No statistically significant differences were found between calculated doses and doses measured at reference points in both dose distribution non-optimised treatment plans and optimised treatment plans.

Conclusions

No statistically significant differences were found in dose values at reference points between doses calculated by the treatment planning system and those measured by TLDs. This proves the consistency between the measurements and the calculations.

Abstract

Aim

The aim of the study was to verify the dose distribution optimisation method in pulsed brachytherapy.

Background

The pulsed-dose rate brachytherapy is a very important method of breast tumour treatment using a standard brachytheraphy equipment. The appropriate dose distribution round an implant is an important issue in treatment planning. Advanced computer systems of treatment planning are equipped with algorithms optimising dose distribution.

Materials and methods

The wax-paraffin phantom was constructed and seven applicators were placed within it. Two treatment plans (non-optimised, optimised) were prepared. The reference points were located at a distance of 5[[ce:hsp sp="0.25"/]]mm from the applicators’ axis. Thermoluminescent detectors were placed in the phantom at suitable 35 chosen reference points.

Results

The dosimetry verification was carried out in 35 reference points for the plans before and after optimisation. Percentage difference for the plan without optimisation ranged from −8.5% to 1.4% and after optimisation from −8.3% to 0.01%. In 16 reference points, the calculated percentage difference was negative (from −8.5% to 1.3% for the plan without optimisation and from −8.3% to 0.8% for the optimised plan). In the remaining 19 points percentage difference was from 9.1% to 1.4% for the plan without optimisation and from 7.5% to 0.01% for the optimised plan.

No statistically significant differences were found between calculated doses and doses measured at reference points in both dose distribution non-optimised treatment plans and optimised treatment plans.

Conclusions

No statistically significant differences were found in dose values at reference points between doses calculated by the treatment planning system and those measured by TLDs. This proves the consistency between the measurements and the calculations.

Get Citation

Keywords

Pulse brachytherapy; Implant; Thermoluminescent detectors; Gafchromic EBT dosimetry

About this article
Title

Measurement verification of dose distributions in pulsed-dose rate brachytherapy in breast cancer

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 18, No 3 (2013)

Pages

139-147

Published online

2013-05-01

DOI

10.1016/j.rpor.2013.03.001

Bibliographic record

Rep Pract Oncol Radiother 2013;18(3):139-147.

Keywords

Pulse brachytherapy
Implant
Thermoluminescent detectors
Gafchromic EBT dosimetry

Authors

Patrycja Mantaj
Grzegorz Zwierzchowski

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