open access

Vol 17, No 6 (2012)
Original research articles
Published online: 2012-11-01
Submitted: 2012-04-04
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Primary squamous cell carcinoma of the breast: A rare case report

Stefania Carbone, Rosabel Lobo Alvarez, Annalisa Lamacchia, Asuncion Almenar Gil, Raquel Martin Hernandez, Jose Luis Lopez Guerra, Hugo Marsiglia
DOI: 10.1016/j.rpor.2012.07.004
·
Rep Pract Oncol Radiother 2012;17(6):363-366.

open access

Vol 17, No 6 (2012)
Original research articles
Published online: 2012-11-01
Submitted: 2012-04-04

Abstract

Background

Squamous cells are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of the breast is an exceptional phenomenon and the management of this type of disease is still debated.

Aim

Clinical outcome assessment of a patient with squamous cell carcinoma of the breast.

Materials and methods

We report a case of primary squamous cell carcinoma of the breast (T1cN0M0) in a 51-years-old woman who underwent breast conserving surgery plus adjuvant chemotherapy and radiation therapy (RT).

Results

With a follow up of 43 months, the patient is alive with no evidence of local or distant recurrence. The patient had Grade 2 acute skin toxicity. No late skin or respiratory toxicity was observed.

Conclusions

Pure primary squamous cell carcinoma of the breast is a rare and aggressive disease, often treatment-refractory. Our case shows that the addition of RT after breast conserving surgery, allows to achieve a high local control without adding severe toxicity. A multidisciplinary approach seems to be the optimal management for early stages in this rare disease.

Abstract

Background

Squamous cells are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of the breast is an exceptional phenomenon and the management of this type of disease is still debated.

Aim

Clinical outcome assessment of a patient with squamous cell carcinoma of the breast.

Materials and methods

We report a case of primary squamous cell carcinoma of the breast (T1cN0M0) in a 51-years-old woman who underwent breast conserving surgery plus adjuvant chemotherapy and radiation therapy (RT).

Results

With a follow up of 43 months, the patient is alive with no evidence of local or distant recurrence. The patient had Grade 2 acute skin toxicity. No late skin or respiratory toxicity was observed.

Conclusions

Pure primary squamous cell carcinoma of the breast is a rare and aggressive disease, often treatment-refractory. Our case shows that the addition of RT after breast conserving surgery, allows to achieve a high local control without adding severe toxicity. A multidisciplinary approach seems to be the optimal management for early stages in this rare disease.

Get Citation

Keywords

Squamous cell carcinoma; Breast cancer; Outcome

About this article
Title

Primary squamous cell carcinoma of the breast: A rare case report

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 17, No 6 (2012)

Pages

363-366

Published online

2012-11-01

DOI

10.1016/j.rpor.2012.07.004

Bibliographic record

Rep Pract Oncol Radiother 2012;17(6):363-366.

Keywords

Squamous cell carcinoma
Breast cancer
Outcome

Authors

Stefania Carbone
Rosabel Lobo Alvarez
Annalisa Lamacchia
Asuncion Almenar Gil
Raquel Martin Hernandez
Jose Luis Lopez Guerra
Hugo Marsiglia

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