open access

Vol 17, No 3 (2012)
Original research articles
Published online: 2012-05-01
Submitted: 2011-10-31
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Underestimation of cancer in case of diagnosis of atypical ductal hyperplasia (ADH) by vacuum assisted core needle biopsy

Karol Polom, Dawid Murawa, Paweł Kurzawa, Michał Michalak, Paweł Murawa
DOI: 10.1016/j.rpor.2012.03.008
·
Rep Pract Oncol Radiother 2012;17(3):129-133.

open access

Vol 17, No 3 (2012)
Original research articles
Published online: 2012-05-01
Submitted: 2011-10-31

Abstract

Background

With the introduction of mammography screening, we are more often dealing with the diagnosis of precancerous and preinvasive breast lesions. An increasing number of patients are observed to show a premalignant change of ADH (atypical ductal hyperplasia). It also involves a wider use of the vacuum assisted core biopsy as a tool for verifying nonpalpable changes identified by mammography.

Aim

This paper describes our experience of 134 cases of ADH diagnosed at Mammotome® vacuum core needle biopsy.

Material and methods

Of 4326 mammotomic biopsies performed at our institution in 2000–2006, ADH was diagnosed in 134 patients (3.1%). Patients underwent surgery to remove the suspected lesion. All histopathological blocks were again reviewed by one pathologist. Clinical, radiological and pathological data were collected for statistical evaluation.

Results

Underestimation of invasive changes occurred in 12 patients (9%). The only clinicopathologic feature of statistical significance radiologically and pathologically was the presence of radial scar in the mammography.

Conclusions

More frequent diagnosis of precancerous changes in the mammotomic breast biopsy forces us to establish a clear clinical practice. The problem is the underestimation of invasive changes. The occurrence of radial scar on mammography for diagnosis of the presence of ADH increases the risk of invasive changes.

Abstract

Background

With the introduction of mammography screening, we are more often dealing with the diagnosis of precancerous and preinvasive breast lesions. An increasing number of patients are observed to show a premalignant change of ADH (atypical ductal hyperplasia). It also involves a wider use of the vacuum assisted core biopsy as a tool for verifying nonpalpable changes identified by mammography.

Aim

This paper describes our experience of 134 cases of ADH diagnosed at Mammotome® vacuum core needle biopsy.

Material and methods

Of 4326 mammotomic biopsies performed at our institution in 2000–2006, ADH was diagnosed in 134 patients (3.1%). Patients underwent surgery to remove the suspected lesion. All histopathological blocks were again reviewed by one pathologist. Clinical, radiological and pathological data were collected for statistical evaluation.

Results

Underestimation of invasive changes occurred in 12 patients (9%). The only clinicopathologic feature of statistical significance radiologically and pathologically was the presence of radial scar in the mammography.

Conclusions

More frequent diagnosis of precancerous changes in the mammotomic breast biopsy forces us to establish a clear clinical practice. The problem is the underestimation of invasive changes. The occurrence of radial scar on mammography for diagnosis of the presence of ADH increases the risk of invasive changes.

Get Citation

Keywords

Atypical ductal hyperplasia; Core biopsy; Breast cancer

About this article
Title

Underestimation of cancer in case of diagnosis of atypical ductal hyperplasia (ADH) by vacuum assisted core needle biopsy

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 17, No 3 (2012)

Pages

129-133

Published online

2012-05-01

DOI

10.1016/j.rpor.2012.03.008

Bibliographic record

Rep Pract Oncol Radiother 2012;17(3):129-133.

Keywords

Atypical ductal hyperplasia
Core biopsy
Breast cancer

Authors

Karol Polom
Dawid Murawa
Paweł Kurzawa
Michał Michalak
Paweł Murawa

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