open access

Vol 16, No 1 (2011)
Original Article
Published online: 2011-01-01
Submitted: 2010-09-01
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Primary mucosal sinonasal melanoma—Case report and review of the literature. The role of complex treatment-surgery and adjuvant radiotherapy

Lena Marinova, Kaloyan Yordanov, Nikolay Sapundgiev
DOI: 10.1016/j.rpor.2010.11.004
·
Rep Pract Oncol Radiother 2011;16(1):40-43.

open access

Vol 16, No 1 (2011)
Original Article
Published online: 2011-01-01
Submitted: 2010-09-01

Abstract

Aim

The place of adjuvant radiotherapy in the treatment of sinonasal melanoma.

Background

Sinonasal mucosal melanoma is a rare disease with poor prognosis and requires a complex treatment. Elective neck dissection in patients with N0 and adjuvant radiotherapy has been a source of controversy. High late regional recurrence rates rise questions about elective irradiation of the neck nodes in patients with N0 stage disease.

Methods

We present our two years’ follow up in a case of locally advanced sinonasal melanoma and literature review of the treatment options for mucosal melanoma.

Results

In locally advanced sinonasal melanoma treated with surgical resection, postoperative radiotherapy and chemotherapy we had local tumor control. Two years later, a regional contralateral recurrence without distant metastasis occurred.

Conclusions

Literature data for frequent neck lymph nodes recurrences justify elective neck dissection. Postoperative elective neck radiotherapy for patients with locally advanced sinonasal melanoma and clinically N0 appears to decrease the rate of late regional recurrences.

Abstract

Aim

The place of adjuvant radiotherapy in the treatment of sinonasal melanoma.

Background

Sinonasal mucosal melanoma is a rare disease with poor prognosis and requires a complex treatment. Elective neck dissection in patients with N0 and adjuvant radiotherapy has been a source of controversy. High late regional recurrence rates rise questions about elective irradiation of the neck nodes in patients with N0 stage disease.

Methods

We present our two years’ follow up in a case of locally advanced sinonasal melanoma and literature review of the treatment options for mucosal melanoma.

Results

In locally advanced sinonasal melanoma treated with surgical resection, postoperative radiotherapy and chemotherapy we had local tumor control. Two years later, a regional contralateral recurrence without distant metastasis occurred.

Conclusions

Literature data for frequent neck lymph nodes recurrences justify elective neck dissection. Postoperative elective neck radiotherapy for patients with locally advanced sinonasal melanoma and clinically N0 appears to decrease the rate of late regional recurrences.

Get Citation

Keywords

Sinonasal melanoma; Complex treatment; Mucosal melanoma; Surgery; Radiotherapy

About this article
Title

Primary mucosal sinonasal melanoma—Case report and review of the literature. The role of complex treatment-surgery and adjuvant radiotherapy

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 16, No 1 (2011)

Pages

40-43

Published online

2011-01-01

DOI

10.1016/j.rpor.2010.11.004

Bibliographic record

Rep Pract Oncol Radiother 2011;16(1):40-43.

Keywords

Sinonasal melanoma
Complex treatment
Mucosal melanoma
Surgery
Radiotherapy

Authors

Lena Marinova
Kaloyan Yordanov
Nikolay Sapundgiev

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