open access

Vol 15, No 4 (2010)
Review
Published online: 2010-07-01
Submitted: 2010-02-24
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Cyberknife: A double edged sword?

Bindhu Joseph, Sanjay S. Supe, Aruna Ramachandra
DOI: 10.1016/j.rpor.2010.05.002
·
Rep Pract Oncol Radiother 2010;15(4):93-97.

open access

Vol 15, No 4 (2010)
Review
Published online: 2010-07-01
Submitted: 2010-02-24

Abstract

The Cyberknife represents a new, frameless stereotactic radiosurgery system which efficiently incorporates advance robotics with computerized image reconstruction to allow highly conformal image guided radiation delivery. This review focus is on the pros and cons of this new radiotherapy tool, its current indications, safety profile and future directions. A literature search of Medline, Pubmed, Biomed, Medscape and Cancer lit database were referred to retrieve relevant data/information. The authors conclude that the use of this system offers an invaluable solution to the treatment of selective tumours/lesions located close to critical structures, salvage of recurrent and metastatic lesions and potential of treatment of selective early stage malignancies like the carcinoma prostate and lung. However, it is still too premature, with insufficient follow up data to advocate it as the treatment of choice in any set up. There are several radiobiological issues that also remain in the greyzone.

Abstract

The Cyberknife represents a new, frameless stereotactic radiosurgery system which efficiently incorporates advance robotics with computerized image reconstruction to allow highly conformal image guided radiation delivery. This review focus is on the pros and cons of this new radiotherapy tool, its current indications, safety profile and future directions. A literature search of Medline, Pubmed, Biomed, Medscape and Cancer lit database were referred to retrieve relevant data/information. The authors conclude that the use of this system offers an invaluable solution to the treatment of selective tumours/lesions located close to critical structures, salvage of recurrent and metastatic lesions and potential of treatment of selective early stage malignancies like the carcinoma prostate and lung. However, it is still too premature, with insufficient follow up data to advocate it as the treatment of choice in any set up. There are several radiobiological issues that also remain in the greyzone.

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Keywords

Cyberknife; Stereotactic radiosurgery; Robotics; Image guided radiotherapy; Pros and cons; Greyzone

About this article
Title

Cyberknife: A double edged sword?

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 15, No 4 (2010)

Pages

93-97

Published online

2010-07-01

DOI

10.1016/j.rpor.2010.05.002

Bibliographic record

Rep Pract Oncol Radiother 2010;15(4):93-97.

Keywords

Cyberknife
Stereotactic radiosurgery
Robotics
Image guided radiotherapy
Pros and cons
Greyzone

Authors

Bindhu Joseph
Sanjay S. Supe
Aruna Ramachandra

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