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Comparison between intensity modulated radiotherapy (IMRT) and 3D tangential beams technique used in patients with early-stage breast cancer who received breast-conserving therapy
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Abstract
Background
The most often found complications in patients with breast cancer who received radiotherapy are cardiac and pulmonary function disorders and development of second malignancies.
Aim
To compare the intensity modulated radiotherapy with the 3D tangential beams technique in respect of dose distribution in target volume and critical organs they generate in patients with early-stage breast cancer who received breast-conserving therapy.
Materials and methods
A dosimetric analysis was performed to assess the three radiotherapy techniques used in each of 10 consecutive patients with early-stage breast cancer treated with breast-conserving therapy. Radiotherapy was planned with the use of all the three techniques: 3D tangential beams with electron boost, IMRT with electron boost, and intensity modulated radiotherapy with simultaneous integrated boost.
Results
The use of the IMRT techniques enables more homogenous dose distribution in target volume. The range of mean and median dose to the heart and lung was lower with the IMRT techniques in comparison to the 3D tangential beams technique. The range of mean dose to the heart amounted to 0.3–3.5[[ce:hsp sp="0.25"/]]Gy for the IMRT techniques and 0.4–4.3 for the tangential beams technique. The median dose to the lung on the irradiated side amounted to 4.9–5[[ce:hsp sp="0.25"/]]Gy for the IMRT techniques and 5.6[[ce:hsp sp="0.25"/]]Gy for the 3D tangential beams technique.
Conclusion
The application of the IMRT techniques in radiotherapy patients with early-stage breast cancer allows to obtain more homogenous dose distribution in target volume, while permitting to reduce the dose to critical organs.
Abstract
Background
The most often found complications in patients with breast cancer who received radiotherapy are cardiac and pulmonary function disorders and development of second malignancies.
Aim
To compare the intensity modulated radiotherapy with the 3D tangential beams technique in respect of dose distribution in target volume and critical organs they generate in patients with early-stage breast cancer who received breast-conserving therapy.
Materials and methods
A dosimetric analysis was performed to assess the three radiotherapy techniques used in each of 10 consecutive patients with early-stage breast cancer treated with breast-conserving therapy. Radiotherapy was planned with the use of all the three techniques: 3D tangential beams with electron boost, IMRT with electron boost, and intensity modulated radiotherapy with simultaneous integrated boost.
Results
The use of the IMRT techniques enables more homogenous dose distribution in target volume. The range of mean and median dose to the heart and lung was lower with the IMRT techniques in comparison to the 3D tangential beams technique. The range of mean dose to the heart amounted to 0.3–3.5[[ce:hsp sp="0.25"/]]Gy for the IMRT techniques and 0.4–4.3 for the tangential beams technique. The median dose to the lung on the irradiated side amounted to 4.9–5[[ce:hsp sp="0.25"/]]Gy for the IMRT techniques and 5.6[[ce:hsp sp="0.25"/]]Gy for the 3D tangential beams technique.
Conclusion
The application of the IMRT techniques in radiotherapy patients with early-stage breast cancer allows to obtain more homogenous dose distribution in target volume, while permitting to reduce the dose to critical organs.
Keywords
Early-stage breast cancer; Radiotherapy; Breast-conserving therapy; Intensity modulated radiotherapy; Tangential beams technique
About this articleTitle
Comparison between intensity modulated radiotherapy (IMRT) and 3D tangential beams technique used in patients with early-stage breast cancer who received breast-conserving therapy
Journal
Reports of Practical Oncology and Radiotherapy
Issue
Pages
79-86
Published online
2010-07-01
DOI
10.1016/j.rpor.2010.06.002
Bibliographic record
Rep Pract Oncol Radiother 2010;15(4):79-86.
Keywords
Early-stage breast cancer
Radiotherapy
Breast-conserving therapy
Intensity modulated radiotherapy
Tangential beams technique
Authors
Beata Sas-Korczyńska
Anna Śladowska
Bożena Rozwadowska-Bogusz
Sonia Dyczek
Jan Lesiak
Anna Kokoszka
Stanisław Korzeniowski