open access

Vol 14, No 4 (2009)
Untitled
Published online: 2009-07-01
Submitted: 2009-07-16
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Dosimetric verification of dose optimisation algorithm during endovascular brachytherapy of the peripheral vessels

Grzegorz ZWIERZCHOWSKI, Julian MALICKI, Janusz SKOWRONEK
DOI: 10.1016/S1507-1367(10)60026-0
·
Rep Pract Oncol Radiother 2009;14(4):114-121.

open access

Vol 14, No 4 (2009)
Untitled
Published online: 2009-07-01
Submitted: 2009-07-16

Abstract

Aim

Dosimetric verification of the dose optimisation model used in endovascular brachytherapy, evaluation of the optimised dose distributions using elaborated indices.

Background

The equipment used for standard radiotherapy is used in vascular brachytherapy for prevention of restenosis after angioplasty.

Material and Method

A paraffin-wax phantom, thermoluminescent detectors and MD-55 Gafchromic® films were used for dose measurements. The edge dose index (EDI), central dose index (CDI) and treatment length index (TLI) were introduced to compare dose distributions calculated and measured.

Results

Obtained values (p>0.05) show no statistically significant differences between calculated doses and measured doses. EDI values showed improvement in dose homogeneity on the edges of the application after optimisation. After optimisation CDI values from 0.9% to 1.6% for calculated and from −1.8% to 3.1% for measured showed improvement in dose homogeneity in the central part of the application. Observed values of TLI from 3% to 21% for calculated doses and from 7% to 24% for doses measured by Gafchromic® films showed increase of RIL for optimised treatment plans.

Conclusions

1/ The designed phantom allowed repeatable dosimetric verification of dose distributions in endovascular brachytherapy. 2/ Measurements with thermoluminescent detectors and Gafchromic films proved the accuracy of the calculation algorithm in endovascular brachytherapy conditions. 3/ Elaborated indices were found to be a useful tool in describing dose homogeneity. They allowed the process of optimisation to be controlled and thus an increase in dose homogeneity by 30% at the edges and by 7% in the middle of the treated volume to be achieved.

Abstract

Aim

Dosimetric verification of the dose optimisation model used in endovascular brachytherapy, evaluation of the optimised dose distributions using elaborated indices.

Background

The equipment used for standard radiotherapy is used in vascular brachytherapy for prevention of restenosis after angioplasty.

Material and Method

A paraffin-wax phantom, thermoluminescent detectors and MD-55 Gafchromic® films were used for dose measurements. The edge dose index (EDI), central dose index (CDI) and treatment length index (TLI) were introduced to compare dose distributions calculated and measured.

Results

Obtained values (p>0.05) show no statistically significant differences between calculated doses and measured doses. EDI values showed improvement in dose homogeneity on the edges of the application after optimisation. After optimisation CDI values from 0.9% to 1.6% for calculated and from −1.8% to 3.1% for measured showed improvement in dose homogeneity in the central part of the application. Observed values of TLI from 3% to 21% for calculated doses and from 7% to 24% for doses measured by Gafchromic® films showed increase of RIL for optimised treatment plans.

Conclusions

1/ The designed phantom allowed repeatable dosimetric verification of dose distributions in endovascular brachytherapy. 2/ Measurements with thermoluminescent detectors and Gafchromic films proved the accuracy of the calculation algorithm in endovascular brachytherapy conditions. 3/ Elaborated indices were found to be a useful tool in describing dose homogeneity. They allowed the process of optimisation to be controlled and thus an increase in dose homogeneity by 30% at the edges and by 7% in the middle of the treated volume to be achieved.

Get Citation

Keywords

endovascular brachytherapy; Gafchromic® films; dose optimisation

About this article
Title

Dosimetric verification of dose optimisation algorithm during endovascular brachytherapy of the peripheral vessels

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 14, No 4 (2009)

Pages

114-121

Published online

2009-07-01

DOI

10.1016/S1507-1367(10)60026-0

Bibliographic record

Rep Pract Oncol Radiother 2009;14(4):114-121.

Keywords

endovascular brachytherapy
Gafchromic® films
dose optimisation

Authors

Grzegorz ZWIERZCHOWSKI
Julian MALICKI
Janusz SKOWRONEK

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