open access

Vol 13, No 6 (2008)
Untitled
Published online: 2008-11-01
Submitted: 2009-02-15
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Dosimetric verification of the dose calculation algorithms in real time prostate brachytherapy

Marta MOCNA, Grzegorz ZWIERZCHOWSKI
DOI: 10.1016/S1507-1367(10)60013-2
·
Rep Pract Oncol Radiother 2008;13(6):275-279.

open access

Vol 13, No 6 (2008)
Untitled
Published online: 2008-11-01
Submitted: 2009-02-15

Abstract

Background

During real time prostate brachytherapy different calculation algorithms can be used which gives the opportunity to modulate the dwell times and positions of the source and consequently the dose distribution and values of therapeutic indices [1].

Aim

The aim of this study was the dosimetric verification (in-phantom) of three optimization algorithms for dose calculation during real-time prostate brachytherapy.

Materials/Methods

Three optimization algorithm were evaluated: geometric optimization (GO), inverse optimization (IO) and blind inverse optimization (BIO). Then treatment plans for the tissue-equivalent phantom were prepared. For each plan the same CTV, organs at risk (OARs: urethra, rectum), number of needles and geometry of implant were used.

Results

Measured mean doses and their standard deviations for GO, IO and BIO were respectively: 11.13 Gy and 0.01 Gy, 15.71 Gy and 0.01 Gy, 14.74 Gy and 0.02 Gy for the urethra and 10.11 Gy and 0.01 Gy, 8.97 Gy and 0.01 Gy, 8.70 Gy and 0.01 Gy for the rectum. Comparison between doses measured by semiconductor detectors and calculated doses revealed differences in the range from 0.10 Gy between doses compared in the urethra for IO and BIO even to 2.46 Gy for GO for the same analyzed organ. For the rectum these differences were between 0.32 and 0.66 Gy.

Conclusions

Qualitative comparative analysis performed for a phantom study for 3D-CBRT prostate treatment proved the correctness of verified optimization algorithms implemented in Oncentra Prostate vs. 3.0.9.

Abstract

Background

During real time prostate brachytherapy different calculation algorithms can be used which gives the opportunity to modulate the dwell times and positions of the source and consequently the dose distribution and values of therapeutic indices [1].

Aim

The aim of this study was the dosimetric verification (in-phantom) of three optimization algorithms for dose calculation during real-time prostate brachytherapy.

Materials/Methods

Three optimization algorithm were evaluated: geometric optimization (GO), inverse optimization (IO) and blind inverse optimization (BIO). Then treatment plans for the tissue-equivalent phantom were prepared. For each plan the same CTV, organs at risk (OARs: urethra, rectum), number of needles and geometry of implant were used.

Results

Measured mean doses and their standard deviations for GO, IO and BIO were respectively: 11.13 Gy and 0.01 Gy, 15.71 Gy and 0.01 Gy, 14.74 Gy and 0.02 Gy for the urethra and 10.11 Gy and 0.01 Gy, 8.97 Gy and 0.01 Gy, 8.70 Gy and 0.01 Gy for the rectum. Comparison between doses measured by semiconductor detectors and calculated doses revealed differences in the range from 0.10 Gy between doses compared in the urethra for IO and BIO even to 2.46 Gy for GO for the same analyzed organ. For the rectum these differences were between 0.32 and 0.66 Gy.

Conclusions

Qualitative comparative analysis performed for a phantom study for 3D-CBRT prostate treatment proved the correctness of verified optimization algorithms implemented in Oncentra Prostate vs. 3.0.9.

Get Citation

Keywords

real time brachytherapy; dose verification; dose measurements; semiconductor detectors

About this article
Title

Dosimetric verification of the dose calculation algorithms in real time prostate brachytherapy

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 13, No 6 (2008)

Pages

275-279

Published online

2008-11-01

DOI

10.1016/S1507-1367(10)60013-2

Bibliographic record

Rep Pract Oncol Radiother 2008;13(6):275-279.

Keywords

real time brachytherapy
dose verification
dose measurements
semiconductor detectors

Authors

Marta MOCNA
Grzegorz ZWIERZCHOWSKI

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