open access

Vol 10, No 2 (2005)
Original Paper
Published online: 2005-01-01
Submitted: 2004-04-02
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Combined treatment for tumours of the base of the skull

Romuald Krajewski, Andrzej Kawecki, Andrzej Kukwa
DOI: 10.1016/S1507-1367(05)71115-9
·
Rep Pract Oncol Radiother 2005;10(2):28-31.

open access

Vol 10, No 2 (2005)
Original Paper
Published online: 2005-01-01
Submitted: 2004-04-02

Abstract

Aim

Tumours situated in the region of the base of the skull are at the limits of possibility for radical resection and in patients with malignant tumours it is necessary to use combined methods of treatment. The purpose of this paper is to evaluate the early results of combined treatment tumours of the base of the skull.

Materials/Methods

Between 1994 and 2004 68 patients with malignant tumours of the base of the skull and 10 with benign tumours were treated by an interdisciplinary group. Treatment included surgery, radiotherapy, and chemotherapy.

Results

After a period of post operative observation (median length 19 months), 32 patients with malignant tumours were without recurrence of disease, 8 lived with the tumour, 21 died as a result of disease progression and 4 died of other causes. Information was unavailable for 3 patients. Among 10 patients with benign tumours, 5 lived without symptoms of disease and 5 with the tumour.

Conclusions

Because of the limited possibilities regarding radical removal of malignant tumours in the region of the base of the skull, combined treatment using radiotherapy, surgery and, in some cases, chemo therapy is standard. Use of aggressive treatments gave local control in about half the patients though further observation is necessary in order to assess later oncological results.

Abstract

Aim

Tumours situated in the region of the base of the skull are at the limits of possibility for radical resection and in patients with malignant tumours it is necessary to use combined methods of treatment. The purpose of this paper is to evaluate the early results of combined treatment tumours of the base of the skull.

Materials/Methods

Between 1994 and 2004 68 patients with malignant tumours of the base of the skull and 10 with benign tumours were treated by an interdisciplinary group. Treatment included surgery, radiotherapy, and chemotherapy.

Results

After a period of post operative observation (median length 19 months), 32 patients with malignant tumours were without recurrence of disease, 8 lived with the tumour, 21 died as a result of disease progression and 4 died of other causes. Information was unavailable for 3 patients. Among 10 patients with benign tumours, 5 lived without symptoms of disease and 5 with the tumour.

Conclusions

Because of the limited possibilities regarding radical removal of malignant tumours in the region of the base of the skull, combined treatment using radiotherapy, surgery and, in some cases, chemo therapy is standard. Use of aggressive treatments gave local control in about half the patients though further observation is necessary in order to assess later oncological results.

Get Citation

Keywords

base of the skull; tumours; surgery; radiotherapy

About this article
Title

Combined treatment for tumours of the base of the skull

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 10, No 2 (2005)

Pages

28-31

Published online

2005-01-01

DOI

10.1016/S1507-1367(05)71115-9

Bibliographic record

Rep Pract Oncol Radiother 2005;10(2):28-31.

Keywords

base of the skull
tumours
surgery
radiotherapy

Authors

Romuald Krajewski
Andrzej Kawecki
Andrzej Kukwa

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