open access

Vol 9, No 6 (2004)
Published online: 2004-01-01
Submitted: 2004-02-25
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Malignant neoplasms of parameningeal region in children – report from two paediatric centres of oncology

Joanna Zawitkowska-Klaczyńska, Ewa Bień, Krzysztof Kątski, Joanna Nurzyńska-Flak, Ewa Dudkiewicz, Jolanta Stefaniak, Ninela Irga, Elżbieta Adamkiewicz-Drożyńska, Anna Ptoszyńska, Anna Balcerska, Czesław Stankiewicz, Jerzy Kowalczyk
DOI: 10.1016/S1507-1367(04)71032-9
·
Rep Pract Oncol Radiother 2004;9(6):229-233.

open access

Vol 9, No 6 (2004)
Published online: 2004-01-01
Submitted: 2004-02-25

Abstract

Subject

To present the analisis of initial clinical symptoms and difficulties in establishing proper diagnosis.

Material and methods

Data on 32 patients with the diagnosis of parameningeal malignant neoplasms were subjected to a retrospective analysis. The study group consisted of 9 girls and 23 boys, at the age of 2–17. The analysis involved clinical symptoms prior to diagnosis, the response to treatment, possible necessary modifications of therapeutic schemes and treatment outcome in particular histological types of parameningeal malignant neoplasms.

Results

The length of history taking in the whole group ranged from 2 weeks to 24 months. The dominant symptoms were directly associated with the local growth of the tumour and its spread to the regional lymph nodes. The extent of spread of the neoplasm in children with STS was found to be: III°in 14 and IV° in 3 patients. All the children with NHL-B were originally assigned to group Baccording to LMBand the patients with lymphoepithelioma to III° (2 children) and IVA° (4 children) according to TNM and AJCC. Among the patients with parameningeal malignant neoplasms, 21/32 children demonstrated CR after the complete treatment, including 8/17 with STS and all patients with NHL-B,4/6 with lymphoepithelioma. Seven patients died: 5 with STS and 2 with lymphoepithelioma. The prognosis of four patients undergoing treatment for STS recurrences is uncertain.

Conclusions

Non-characteristic initial clinical symptoms and signs of parameningeal tumours, often suggestive of an inflammatory process, results in diagnostic difficulties. Since radical resection of parameningeal neoplasms in children is impossible, the prognosis depends on the neoplasm's sensitivity to chemo- and radiotherapy.

Abstract

Subject

To present the analisis of initial clinical symptoms and difficulties in establishing proper diagnosis.

Material and methods

Data on 32 patients with the diagnosis of parameningeal malignant neoplasms were subjected to a retrospective analysis. The study group consisted of 9 girls and 23 boys, at the age of 2–17. The analysis involved clinical symptoms prior to diagnosis, the response to treatment, possible necessary modifications of therapeutic schemes and treatment outcome in particular histological types of parameningeal malignant neoplasms.

Results

The length of history taking in the whole group ranged from 2 weeks to 24 months. The dominant symptoms were directly associated with the local growth of the tumour and its spread to the regional lymph nodes. The extent of spread of the neoplasm in children with STS was found to be: III°in 14 and IV° in 3 patients. All the children with NHL-B were originally assigned to group Baccording to LMBand the patients with lymphoepithelioma to III° (2 children) and IVA° (4 children) according to TNM and AJCC. Among the patients with parameningeal malignant neoplasms, 21/32 children demonstrated CR after the complete treatment, including 8/17 with STS and all patients with NHL-B,4/6 with lymphoepithelioma. Seven patients died: 5 with STS and 2 with lymphoepithelioma. The prognosis of four patients undergoing treatment for STS recurrences is uncertain.

Conclusions

Non-characteristic initial clinical symptoms and signs of parameningeal tumours, often suggestive of an inflammatory process, results in diagnostic difficulties. Since radical resection of parameningeal neoplasms in children is impossible, the prognosis depends on the neoplasm's sensitivity to chemo- and radiotherapy.

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Keywords

lymphoma; lymphoepithelioma; soft tissue sarcoma; children

About this article
Title

Malignant neoplasms of parameningeal region in children – report from two paediatric centres of oncology

Journal

Reports of Practical Oncology and Radiotherapy

Issue

Vol 9, No 6 (2004)

Pages

229-233

Published online

2004-01-01

DOI

10.1016/S1507-1367(04)71032-9

Bibliographic record

Rep Pract Oncol Radiother 2004;9(6):229-233.

Keywords

lymphoma
lymphoepithelioma
soft tissue sarcoma
children

Authors

Joanna Zawitkowska-Klaczyńska
Ewa Bień
Krzysztof Kątski
Joanna Nurzyńska-Flak
Ewa Dudkiewicz
Jolanta Stefaniak
Ninela Irga
Elżbieta Adamkiewicz-Drożyńska
Anna Ptoszyńska
Anna Balcerska
Czesław Stankiewicz
Jerzy Kowalczyk

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