Differential diagnosis of inflammatory myopathies, Becker muscular dystrophy (BMD) in a 10-year-old boy
Abstract
The article presents the case of a 10-year-old boy referred for rheumatic diagnosis with suspected inflammation of the muscles without the presence of skin lesions in which Becker muscular dystrophy (BMD) was diagnosed. In cases of isolated myopathy without skin lesions, it is necessary to exclude the neurogenic origin of muscle damage, muscular dystrophies and myasthenic disorders, additionally, viral, bacterial, parasitic infectious myopathy should be considered as a result of hormonal disturbances, drug poisoning and metabolic and electrolyte disorders. Becker muscular dystrophy is a genetically conditioned disease that causes progressive and irreversible muscular atrophy, and is inherited in a recessive manner in gender-related intercourse. The incidence is around 1.5–6/100,000 births of boys. Becker dystrophy is a milder form of the Duchenne dystrophy type (DMD). The first symptoms occur at the age of 6–12 years. They include duck feet, problems with running and climbing stairs. The disease is progressive, initially affects the skeletal muscles, then also the myocardium leading to cardiomyopathy. Loss of ability to move independently occurs later, only after the age of 16. The average survival period is 45 years.
Forum Reumatol. 2019, tom 5, nr 1: 43–46
Keywords: myositismuscular dystrophymolecular diagnostics
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