Vol 17, No 4 (2024)
Review paper
Published online: 2024-12-19

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The role of viruses in the pathogenesis of skin cancer in patients with chronic kidney disease and kidney transplant recipients

Joanna Musialik1, Andrzej Więcek1
DOI: 10.5603/rdatf.104115
Renal Disease and Transplantation Forum 2024;17(4):142-147.

Abstract

In patients with chronic kidney disease and after
kidney transplantation, the risk of cancer increases
significantly due to the impaired function of the
immune system. It is caused by the presence of
uremic toxins or the use of immunosuppressive
drugs and recurrent infections. It was found that in
both groups of patients the most common type of
cancer are non-melanoma skin cancers and among
them squamous cell carcinoma (sSCC). Viruses remain
the key carcinogens in both sSCC and other
primary skin cancers.

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