Candida arteritis after kidney transplantation — a case series
, 1, 2, 3
Abstract
We present 3 cases of candida arteritis in kidney recipients. It is an uncommon but life-threatening complication of kidney transplantation. The most common cause is a contamination of preservation fluid with fungal pathogens from donor's intestine. Early diagnosis is rare as initially symptoms are unspecific and culture from preservation fluid is in most cases negative. Often the first symptom is a sudden arterial rupture what can lead to hemorrhagic shock. We present 3 cases of candida arteritis in kidney transplant recipients. The first reported patient suffered from transplant renal artery thrombosis and subsequent iliac artery rupture. The second recipient presented mycotic pseudoaneurysm of transplant renal artery. The third reported patient suffered from leakage from transplant renal artery anastomosis and rupture of inferior epigastric artery with numerous surgical complications. All presented patients lost transplanted kidneys and returned to hemodialysis.
Keywords: candida arteritiskidney transplantationfungal infections
Article available in PDF format
View PDFReferences
- Osmán I, Barrero R, León E, et al. Mycotic pseudoaneurysm following a kidney transplant: A case report and review of the literature. Pediatric Transplantation. 2009; 13(5): 615–619.
- Taghavi M, Fard AS, Mehrsai R, et al. Late Onset Anastomotic Pseudoaneurysm of Renal Allograft Artery: Case Report, Diagnosis, and Treatment. Transplantation Proceedings. 2005; 37(10): 4297–4299.
- Neofytos D, Fishman JA, Horn D, et al. Epidemiology and outcome of invasive fungal infections in solid organ transplant recipients. Transplant Infectious Disease. 2010; 12(3): 220–229.
- Dębska‐Ślizień A, Chrobak Ł, Bzoma B, et al. Candida arteritis in kidney transplant recipients: case report and review of the literature. Transplant Infectious Disease. 2015; 17(3): 449–455.
- Albano L, Bretagne S, Mamzer‐Bruneel M, et al. Evidence That Graft‐Site Candidiasis after Kidney Transplantation Is Acquired during Organ Recovery: A Multicenter Study in France. Clinical Infectious Diseases. 2009; 48(2): 194–202.
- Calviño J, Romero R, Pintos E, et al. Renal artery rupture secondary to pretransplantation Candida contamination of the graft in two different recipients. American Journal of Kidney Diseases. 1999; 33(1): E1–E5.
- Cabral D, Penumutchu S, Norris C, et al. Microbial competition between Escherichia coli and Candida albicans reveals a soluble fungicidal factor. Microbial Cell. 2018; 5(5): 249–255.
- Tang M, Xu X, Shen B, et al. Fifty‐one cases of fungal arteritis after kidney transplantation: A case report and review of the literature. Transplant Infectious Disease. 2017; 19(6).
