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Tryptophan level is related to personality, not to diagnosis or suicidality, in psychiatric inpatients — a pilot study
, 2, 3, 4, 5, 6, 5
Afiliacje- Klinika Psychiatryczna, Wydział Nauk o Zdrowiu, Warszawski Uniwersytet Medyczny, Warszawa
- Strefa Spotkań, Pruszków
- Samodzielna Pracownia Stomatologii Doświadczalnej, Uniwersytet Medyczny w Białymstoku, Białystok
- Zakład Higieny, Epidemiologii i Ergonomii, Uniwersytet Medyczny w Białymstoku, Białystok
- Klinika Psychiatrii, Uniwersytet Medyczny w Białymstoku, Białystok
- Studenckie Koło Naukowe Psychiatrii, Klinika Psychiatryczna, Wydział Nauk o Zdrowiu, Warszawski Uniwersytet Medyczny, Warszawa
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Streszczenie
According to research studies the deficiency of tryptophan is associated with depression and suicidal behaviours. The objective of this study is to identify the impact of tryptophan on psychological portrait in patients hospitalized psychiatrically. This pilot study included 59 participants, aged 19–65, psychiatrically hospitalized. The Adjective Checklist (ACL) was used to identify personality traits of the subjects. Blood specimens were collected and measured for tryptophan, N-formylkynurenine and kynurenine. The Spearman’s rho was used to analyse the relation between psychological picture and biochemical measures. The conducted statistical analysis revealed several significant relationships between personality traits and fluorescence of tryptophan and N-formylkynurenine. No significant correlations between tryptophan levels and suicidality or diagnosis were disclosed. Outcomes are discussed in terms of potential influence of genetic factors, both on personality and tryptophan levels.
Streszczenie
According to research studies the deficiency of tryptophan is associated with depression and suicidal behaviours. The objective of this study is to identify the impact of tryptophan on psychological portrait in patients hospitalized psychiatrically. This pilot study included 59 participants, aged 19–65, psychiatrically hospitalized. The Adjective Checklist (ACL) was used to identify personality traits of the subjects. Blood specimens were collected and measured for tryptophan, N-formylkynurenine and kynurenine. The Spearman’s rho was used to analyse the relation between psychological picture and biochemical measures. The conducted statistical analysis revealed several significant relationships between personality traits and fluorescence of tryptophan and N-formylkynurenine. No significant correlations between tryptophan levels and suicidality or diagnosis were disclosed. Outcomes are discussed in terms of potential influence of genetic factors, both on personality and tryptophan levels.
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Słowa kluczowe
psychiatry; depression; tryptophan
Informacje o artykuleTytuł
Tryptophan level is related to personality, not to diagnosis or suicidality, in psychiatric inpatients — a pilot study
Czasopismo
Numer
Typ artykułu
Krótkie doniesienie naukowe
Strony
135-139
Opublikowany online
2023-10-06
Wyświetlenia strony
425
Wyświetlenia/pobrania artykułu
165
DOI
Rekord bibliograficzny
Psychiatria 2023;20(3):135-139.
Słowa kluczowe
psychiatry
depression
tryptophan
Autorzy
Tytus Jacek Koweszko
Jacek Gierus
Anna Zalewska
Mateusz Maciejczyk
Napoleon Waszkiewicz
Małgorzata Tobiaszewska
Agata Szulc
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