open access

Vol 13, No 2 (2016)
Review paper
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Pregabalin In the treatment of generalized anxiety disorder

Dariusz Wasilewski
Psychiatria 2016;13(2):74-76.

open access

Vol 13, No 2 (2016)
Prace poglądowe - nadesłane

Abstract

The aim of this review is to estimate the efficacy and safety of pregabalin for the treatment of generalized anxiety disorder (GAD). Pregabalin efficacy has been consistently demonstrated across the licensed dose range of 150−600 mg/day. Efficacy has been reported for pregabalin monotherapy in patients with GAD, patients with other anxiety disorders, and for adjunctive therapy when added to a selective serotonin reuptake inhibitor or serotonin-norepinephrine reuptake inhibitor in patients who have failed to respond to an initial course of antidepressant therapy. Pregabalin is safety and well tolerated, also in elderly patients. The two most common adverse events with pregabalin are somnolence and dizziness, both of which appear to be dose-related. A review of available evidence indicates that pregabalin is consistently effective treatment for GAD, with a unique mechanism of action that makes it a useful addition to the therapeutic armamentarium.

Abstract

The aim of this review is to estimate the efficacy and safety of pregabalin for the treatment of generalized anxiety disorder (GAD). Pregabalin efficacy has been consistently demonstrated across the licensed dose range of 150−600 mg/day. Efficacy has been reported for pregabalin monotherapy in patients with GAD, patients with other anxiety disorders, and for adjunctive therapy when added to a selective serotonin reuptake inhibitor or serotonin-norepinephrine reuptake inhibitor in patients who have failed to respond to an initial course of antidepressant therapy. Pregabalin is safety and well tolerated, also in elderly patients. The two most common adverse events with pregabalin are somnolence and dizziness, both of which appear to be dose-related. A review of available evidence indicates that pregabalin is consistently effective treatment for GAD, with a unique mechanism of action that makes it a useful addition to the therapeutic armamentarium.

Get Citation

Keywords

pregabalin, treatment, generalized anxiety disorder

About this article
Title

Pregabalin In the treatment of generalized anxiety disorder

Journal

Psychiatria (Psychiatry)

Issue

Vol 13, No 2 (2016)

Article type

Review paper

Pages

74-76

Bibliographic record

Psychiatria 2016;13(2):74-76.

Keywords

pregabalin
treatment
generalized anxiety disorder

Authors

Dariusz Wasilewski

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