open access

Vol 4, No 2 (2007)
Research paper
Published online: 2007-05-22
Get Citation

Working memory and executive functions disorders in schizophrenic patients in partial remission of psychopathological symptoms

Beata Hintze, Jacek Wciórka, Alina Borkowska
Psychiatria 2007;4(2):45-52.

open access

Vol 4, No 2 (2007)
Prace oryginalne - nadesłane
Published online: 2007-05-22

Abstract


Introduction. The aim of the study was to assess the level and character of cognitive dysfunctions connected with prefrontal cortex activity in patients with schizophrenia in partial remission of psychopathological symptoms and evaluation of connections between demographic and clinical factors of the illness and cognitive dysfunctions.
Material and methods. 45 patients with schizophrenia were included in the study (28 male and 17 female), aged 18-46 (mean 27 ± 7) years during partial remission of psychopathological symptoms (PANSS < 70). The control group consisted with 35 age, gender and education matched healthy persons (13 male i 22 female), aged 21-49 (mean 30 ± 8) years. To assess the intensity of psychopathological symptoms the PANSS scale was used, neuropsychological assessment included Wisconsin Card Sorting Test (WCST), N-back test and Stroop test from Vienna Tests Battery.
Results and conclusions. In schizophrenic patients in partial remission, the significant dysfunctions of working memory and executive functions, connected with prefrontal cortex dysfunctions compared to healthy controls were foud. The higher number of hospitalization correlated with worse performance on N-back test, and the lover level of education was assessed with the worse results on WCST (percentage of perseverative errors and lower number of correct completed category) and the lower number of correct reactions on N-back test.

Abstract


Introduction. The aim of the study was to assess the level and character of cognitive dysfunctions connected with prefrontal cortex activity in patients with schizophrenia in partial remission of psychopathological symptoms and evaluation of connections between demographic and clinical factors of the illness and cognitive dysfunctions.
Material and methods. 45 patients with schizophrenia were included in the study (28 male and 17 female), aged 18-46 (mean 27 ± 7) years during partial remission of psychopathological symptoms (PANSS < 70). The control group consisted with 35 age, gender and education matched healthy persons (13 male i 22 female), aged 21-49 (mean 30 ± 8) years. To assess the intensity of psychopathological symptoms the PANSS scale was used, neuropsychological assessment included Wisconsin Card Sorting Test (WCST), N-back test and Stroop test from Vienna Tests Battery.
Results and conclusions. In schizophrenic patients in partial remission, the significant dysfunctions of working memory and executive functions, connected with prefrontal cortex dysfunctions compared to healthy controls were foud. The higher number of hospitalization correlated with worse performance on N-back test, and the lover level of education was assessed with the worse results on WCST (percentage of perseverative errors and lower number of correct completed category) and the lower number of correct reactions on N-back test.
Get Citation

Keywords

schizophrenia; working memory; executive functions

About this article
Title

Working memory and executive functions disorders in schizophrenic patients in partial remission of psychopathological symptoms

Journal

Psychiatria (Psychiatry)

Issue

Vol 4, No 2 (2007)

Article type

Research paper

Pages

45-52

Published online

2007-05-22

Bibliographic record

Psychiatria 2007;4(2):45-52.

Keywords

schizophrenia
working memory
executive functions

Authors

Beata Hintze
Jacek Wciórka
Alina Borkowska

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Wydawcą serwisu jest Via Medica sp. z o.o. sp. komandytowa, ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl