Tom 4, Nr 4 (2007)
Artykuł przeglądowy
Opublikowany online: 2007-10-31
Interakcja czynników genetycznych i środowiskowych w schizofrenii
Joanna Hauser
Psychiatria 2007;4(4):153-159.
Tom 4, Nr 4 (2007)
Artykuły przeglądowe
Opublikowany online: 2007-10-31
Streszczenie
The purpose of this article is to present research that test hypotheses of gene-environment interaction (GxE) in
schizophrenia. Family, twins studies indicate that genetic factor cannot explain the entirety of liability to schizophrenia,
and that the environment plays a non-trivial role. Risk to overt schizophrenia is then an integrated function
of numerous predisposing genes, environmental factors and their interactions. Gene-environment interactions
were thought to be rare in psychiatry, but now clinical findings of measured GxE are emerging. The authors
synthesize findings of studies implicating genes, cannabis use, brain injury, migration, obstetric complications as
risk factor for the development of schizophrenia. Second, we summarize the emerging evidence about GxE in
schizophrenia, we also describe strategies that may be used to further studies of GxE
Streszczenie
The purpose of this article is to present research that test hypotheses of gene-environment interaction (GxE) in
schizophrenia. Family, twins studies indicate that genetic factor cannot explain the entirety of liability to schizophrenia,
and that the environment plays a non-trivial role. Risk to overt schizophrenia is then an integrated function
of numerous predisposing genes, environmental factors and their interactions. Gene-environment interactions
were thought to be rare in psychiatry, but now clinical findings of measured GxE are emerging. The authors
synthesize findings of studies implicating genes, cannabis use, brain injury, migration, obstetric complications as
risk factor for the development of schizophrenia. Second, we summarize the emerging evidence about GxE in
schizophrenia, we also describe strategies that may be used to further studies of GxE
Słowa kluczowe
schizofrenia; interakcja czynników genetycznych i środowiskowych
Tytuł
Interakcja czynników genetycznych i środowiskowych w schizofrenii
Czasopismo
Psychiatria
Numer
Tom 4, Nr 4 (2007)
Typ artykułu
Artykuł przeglądowy
Strony
153-159
Opublikowany online
2007-10-31
Wyświetlenia strony
2356
Wyświetlenia/pobrania artykułu
6013
Rekord bibliograficzny
Psychiatria 2007;4(4):153-159.
Słowa kluczowe
schizofrenia
interakcja czynników genetycznych i środowiskowych