open access

Vol 5, No 1 (2008)
Research paper
Published online: 2008-03-12
Get Citation

Deficit of working memory and cognitive functions in partially remitted unipolar depression and bipolar disorder

Marcin Jaracz, Lidia Cierpiałkowska, Alina Borkowska
Psychiatria 2008;5(1):23-29.

open access

Vol 5, No 1 (2008)
Prace oryginalne - nadesłane
Published online: 2008-03-12

Abstract


Introduction. Cognitive dysfunctions in affective disorders are important element their clinical pictures. The aim of the study was to compare the abilities on different aspects of working memory and executive functions in bipolar and unipolar remitted patients in comparison to and healthy controls.
Material and methods. There were 45 patients examined, 29 female and 16 male, aged 46 ± 9. Fourteen patients met the diagnostic criteria of unipolar and 31 of bipolar affective disorder, in partial remission. The control group consisted of 45 age, sex and education years matched healthy subjects. Cognitive assessment was made with Wisconsin Card Sorting Test (WCST), Stroop test and Trail Making Test (TMT). Psychometric assessment was done with Beck Depression Inventory.
Results. Both groups of patients performed worse on all neuropsychological measures compared to healthy subjects. Unipolar patients performed worse in Stroop test compared to bipolar patients. There was a correlation between duration of illness and the level of performance in WCST and Stroop test in the bipolar group. A correlation between age and performance in TMT test was observed in both groups of patients. The score in Beck inventory correlated with cognitive performance in unipolar patients.
Conclusions. Working memory and executive dysfunctions in bipolar and unipolar affective illnesses persisted in partial remission period but show different character. Different profile of these dysfunctions may indicate different etiopathogenetic mechanism.
Psychiatry 2008; 5: 23–29

Abstract


Introduction. Cognitive dysfunctions in affective disorders are important element their clinical pictures. The aim of the study was to compare the abilities on different aspects of working memory and executive functions in bipolar and unipolar remitted patients in comparison to and healthy controls.
Material and methods. There were 45 patients examined, 29 female and 16 male, aged 46 ± 9. Fourteen patients met the diagnostic criteria of unipolar and 31 of bipolar affective disorder, in partial remission. The control group consisted of 45 age, sex and education years matched healthy subjects. Cognitive assessment was made with Wisconsin Card Sorting Test (WCST), Stroop test and Trail Making Test (TMT). Psychometric assessment was done with Beck Depression Inventory.
Results. Both groups of patients performed worse on all neuropsychological measures compared to healthy subjects. Unipolar patients performed worse in Stroop test compared to bipolar patients. There was a correlation between duration of illness and the level of performance in WCST and Stroop test in the bipolar group. A correlation between age and performance in TMT test was observed in both groups of patients. The score in Beck inventory correlated with cognitive performance in unipolar patients.
Conclusions. Working memory and executive dysfunctions in bipolar and unipolar affective illnesses persisted in partial remission period but show different character. Different profile of these dysfunctions may indicate different etiopathogenetic mechanism.
Psychiatry 2008; 5: 23–29
Get Citation

Keywords

bipolar disorder; unipolar depression; working memory; executive functions

About this article
Title

Deficit of working memory and cognitive functions in partially remitted unipolar depression and bipolar disorder

Journal

Psychiatria (Psychiatry)

Issue

Vol 5, No 1 (2008)

Article type

Research paper

Pages

23-29

Published online

2008-03-12

Bibliographic record

Psychiatria 2008;5(1):23-29.

Keywords

bipolar disorder
unipolar depression
working memory
executive functions

Authors

Marcin Jaracz
Lidia Cierpiałkowska
Alina Borkowska

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Wydawcą serwisu jest Via Medica sp. z o.o. sp. komandytowa, ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl