open access

Vol 9, No 1 (2012)
Review paper
Published online: 2012-05-28
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Asenapine — a new atypical antipsychotic

Adam Wysokiński, Iwona Kłoszewska
Psychiatria 2012;9(1):27-35.

open access

Vol 9, No 1 (2012)
Prace poglądowe - nadesłane
Published online: 2012-05-28

Abstract

The authors present a review of current knowledge on asenapine, a new atypical antipsychotic agent, which has recently become available in Poland. Sublingual form was developed to overcome a disadvantageous pharmacokinetic profile for oral administration. Asenapine is used in the treatment of schizophrenia and mania or mixed episodes in the course of bipolar affective disorder. Clinical trials confirm its efficacy and safety. Asenapine major advantage is its neutral metabolic profile combined with antipsychotic and antimanic efficacy comparable to other atypicals. Improvements in negative symptoms and cognitive deficits in the course of schizophrenia were noted during the treatment with asenapine. The most common side effects of asenapine include somnolence, insomnia, nausea and anxiety.

Abstract

The authors present a review of current knowledge on asenapine, a new atypical antipsychotic agent, which has recently become available in Poland. Sublingual form was developed to overcome a disadvantageous pharmacokinetic profile for oral administration. Asenapine is used in the treatment of schizophrenia and mania or mixed episodes in the course of bipolar affective disorder. Clinical trials confirm its efficacy and safety. Asenapine major advantage is its neutral metabolic profile combined with antipsychotic and antimanic efficacy comparable to other atypicals. Improvements in negative symptoms and cognitive deficits in the course of schizophrenia were noted during the treatment with asenapine. The most common side effects of asenapine include somnolence, insomnia, nausea and anxiety.
Get Citation

Keywords

asenapine; antipsychotic agents; schizophrenia; bipolar disorder

About this article
Title

Asenapine — a new atypical antipsychotic

Journal

Psychiatria (Psychiatry)

Issue

Vol 9, No 1 (2012)

Article type

Review paper

Pages

27-35

Published online

2012-05-28

Bibliographic record

Psychiatria 2012;9(1):27-35.

Keywords

asenapine
antipsychotic agents
schizophrenia
bipolar disorder

Authors

Adam Wysokiński
Iwona Kłoszewska

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