Przemijająca niepamięć całkowita — zagadka z brakującym elementem
Streszczenie
Pomimo licznych osiągnięć diagnostyczno-terapeutycznych, jakie dokonały się w neurologii na przestrzeni ostatnich dekad, przemijająca niepamięć całkowita (TGA) pozostaje w dalszym ciągu jedną z najbardziej enigmatycznych jednostek chorobowych w praktyce neurologicznej. Wysunięto liczne hipotezy próbujące wytłumaczyć patogenezę tego zjawiska, jednak do dzisiaj nie udało się ustalić jednoznacznego patomechanizmu leżącego u jego podłoża. Choroba ma łagodny charakter i nie wiąże się z istotnym ryzykiem dla zdrowia i życia pacjenta, jednak jej obraz kliniczny sprawia, że jest unikatowa. W artykule przedstawiono najnowsze doniesienia na temat epidemiologii, etiologii, diagnostyki i leczenia TGA oraz krótko opisano podstawy anatomiczne i fizjologiczne procesu zapamiętywania.
Słowa kluczowe: TGAprzemijająca niepamięć całkowitaprzejściowa amnezja globalnatransient global amnesiaCSDcerebral spreading depression
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