Tom 13, Nr 2 (2017)
Opis przypadku
Opublikowany online: 2017-07-08
Wyświetlenia strony
2310
Wyświetlenia/pobrania artykułu
21596
Toksyczne uszkodzenie mózgu z dominującym zespołem pozapiramidowym i amnestycznym w następstwie zatrucia tlenkiem węgla
Pol. Przegl. Neurol 2017;13(2):82-87.
Streszczenie
Tlenek węgla (CO) jest bezbarwnym, bezwonnym, pozbawionym smaku i właściwości drażniących gazem, który preferencyjnie łączy się z hemoglobiną z powinowactwem 200-230 razy silniejszym niż tlen. Powoduje uszkodzenie narządów najbardziej wrażliwych na niedotlenienie, w obrębie układu nerwowego przede wszystkim mózgowia. Zatrucie CO manifestuje się zróżnicowanym obrazem klinicznym, co przy braku ukierunkowanego wywiadu chorobowego może istotnie utrudnić ustalenie właściwego rozpoznania.
Przedstawiono 66-letnią kobietę, u której w następstwie zatrucia tlenkiem węgla rozwinęła się encefalopatia z silnie wyrażonym zespołem pozapiramidowym i amnestycznym. W MRI mózgowia w obrazach T1-zależnych uwidoczniono charakterystyczne, hiperintensywne obszary, odpowiadające krwotocznej martwicy obu gałek bladych.
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