Vol 69, No 6 (2011)
Reviews
Published online: 2011-06-15
Stem cells in cardiological clinical trials
DOI: 10.33963/v.kp.79291
Kardiol Pol 2011;69(6):601-609.
Abstract
Stem cell-based therapy is a novel therapeutic strategy introduced into cardiology, although there are not any established
standards within the stem/progenitor cell type employed, their preparation, rout of administration as well as methods controlling
the pathophysiological and clinical parameters after the cell application. The aim of the present work was a complex metaanalysis
of the clinical trials carried out in this field. Over 1000 patients with myocardial infarction as well as circulatory failure have
been treated with stem cell-based therapy so far, but the obtained results are not concordant. Progress within cell biology and
biotechnology give hopes for development of more effective therapeutic approaches. Identification and isolation of cardiac-
-specific stem/progenitor cells may deliver new perspectives for such therapy in the nearest future.
Kardiol Pol 2011; 69, 6: 601–609
Kardiol Pol 2011; 69, 6: 601–609
Keywords: stem/progenitor cellsmyocardial infarctionclinical trialsstem cell-based therapy