Online first
Original article
Published online: 2025-02-18

open access

Page views 65
Article views/downloads 40
Get Citation

Connect on Social Media

Connect on Social Media

Percutaneous coronary intervention and coronary artery bypass grafting in myocardial infarction complicated by cardiogenic shock

Mariusz Gąsior1, Mateusz Tajstra1, Marek Deja2, Robert Gil3, Jerzy Pacholewicz4, Stanisław Bartuś5, Marek Jasiński6, Marek Gierlotka7, Romuald Cichoń8, Adam Witkowski9, Jan Rogowski10, Dariusz Dudek11, Zdzisław Tobota12, Wojciech Wojakowski13, Kazimierz Widenka14, Krzysztof Milewski15, Bohdan Maruszewski16, Janina Stępińska171819, Grzegorz Hirnle20, Jacek Legutko21, Piotr Suwalski2223, Przemysław Trzeciak1, Piotr Przybyłowski20, Tomasz Hrapkowicz20

Abstract

Background: Cardiogenic shock (CS) remains the leading cause of poor prognosis in patients with acute myocardial infarction (AMI), sustaining a high mortality rate of 40 to 50% within 30 days.
Aims: In this unique analysis of two national all-comers, real-life registries including patients with AMI complicated by CS, for whom early revascularization was planned, we aimed to compare the effect of percutaneous coronary revascularization (PCI) and coronary artery bypass grafting (CABG) on 30-day and 1-year all-cause mortality.
Methods: The study included consecutive patients with AMI complicated by CS included in the Polish Registry of Acute Coronary Syndromes (PL-ACS) and the Polish National Registry of Cardiac Surgical Procedures (KROK), treated with PCI and CABG, respectively. A layered analysis and Kaplan–Meier curves were used in the propensity score matched (PSM) groups.
Results: Between 2006 and 2022, a total of 1970 patients with AMI complicated by CS, with known coronary anatomy were included in PL-ACS and KROK registries. 1376 (69.8%) had PCI and 594 (30.2%) had CABG. Following a 1:1 PSM, a total of 822 patients were finally included in the analysis. The mortality rates were 48.2% in the PCI group compared with 38.6% in the CABG group at 30 days (P <0.001) and 53.5% compared with 41.1%, respectively, at 1 year (P <0.001).
Conclusions: Among patients with AMI affected by CS, those qualified to be treated with CABG had a higher survival rate at 30 days and one year as compared to those treated with PCI.

Article available in PDF format

View PDF Download PDF file

References

  1. Harjola VP, Lassus J, Sionis A, et al. CardShock Study Investigators, GREAT network. Clinical picture and risk prediction of short-term mortality in cardiogenic shock. Eur J Heart Fail. 2015; 17(5): 501–509.
  2. van Diepen S, Katz JN, Albert NM, et al. Contemporary management of cardiogenic shock: a scientific statement from the American Heart Association. Circulation. 2017; 136(16): e232–e268.
  3. Thiele H, Ohman EM, de Waha-Thiele S, et al. Management of cardiogenic shock complicating myocardial infarction: an update 2019. Eur Heart J. 2019; 40(32): 2671–2683.
  4. Gąsior M, Tajstra M, Cieśla D, et al. Management of patients with myocardial infarction complicated by cardiogenic shock: Data from a comprehensive all-comer administrative database covering a population of 4.4 million. Kardiol Pol. 2024; 82(5): 534–536.
  5. Thiele H, Zeymer U, Neumann FJ, et al. Intraaortic balloon support for myocardial infarction with cardiogenic shock. N Engl J Med. 2012; 367(14): 1287–1296.
  6. Thiele H, Akin I, Sandri M, et al. PCI strategies in patients with acute myocardial infarction and cardiogenic shock. N Engl J Med. 2017; 377(25): 2419–2432.
  7. Thiele H, Zeymer U, Akin I, et al. Extracorporeal life support in infarct-related cardiogenic shock. N Engl J Med. 2023; 389(14): 1286–1297.
  8. White HD, Assmann SF, Sanborn TA, et al. Comparison of percutaneous coronary intervention and coronary artery bypass grafting after acute myocardial infarction complicated by cardiogenic shock: results from the Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock (SHOCK) trial. Circulation. 2005; 112(13): 1992–2001.
  9. Mehta RH, Lopes RD, Ballotta A, et al. Percutaneous coronary intervention or coronary artery bypass surgery for cardiogenic shock and multivessel coronary artery disease? Am Heart J. 2010; 159(1): 141–147.
  10. Neumann FJ, Sousa-Uva M, Ahlsson A, et al. 2018 ESC/EACTS guidelines on myocardial revascularization. Eur Heart J. 2019; 40: 87–165.
  11. Lawton JS, Tamis-Holland JE, Bangalore S, et al. 2021 ACC/AHA/SCAI Guideline for coronary artery revascularization: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. J Am Coll Cardiol. 2022; 79: 197–215.
  12. Kolte D, Khera S, Aronow WS, et al. Trends in incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction in the United States. J Am Heart Assoc. 2014; 3(1): e000590.
  13. Poloński L, Gasior M, Gierlotka M, et al. Polish Registry of Acute Coronary Syndromes (PL-ACS). Characteristics, treatments and outcomes of patients with acute coronary syndromes in Poland. Kardiol Pol. 2007; 65: 861–874.
  14. Knapik P, Knapik M, Zembala MO, et al. In-hospital and mid-term outcomes in patients reoperated on due to bleeding following coronary artery surgery (from the KROK Registry). Interact Cardiovasc Thorac Surg. 2019; 29(2): 237–243.
  15. Thygesen K, Alpert JS, Jaffe AS, et al. Fourth universal definition of myocardial infarction. Eur Heart J. 2019; 40(3): 237–269.
  16. Austin PC. Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. Pharm Stat. 2011; 10(2): 150–161.
  17. Baltar VT, Sousa CA, Westphal MF. Mahalanobis' distance and propensity score to construct a controlled matched group in a Brazilian study of health promotion and social determinants. Rev Bras Epidemiol. 2014; 17(3): 668–679.
  18. Hollenberg SM, Kavinsky CJ, Parrillo JE. Cardiogenic shock. Ann Intern Med. 1999; 131(1): 47–59.
  19. Hochman JS, Sleeper LA, Webb JG, et al. Early revascularization in acute myocardial infarction complicated by cardiogenic shock. N Engl J Med. 1999; 341(9): 625–634.
  20. Aissaoui N, Puymirat E, Delmas C, et al. Trends in cardiogenic shock complicating acute myocardial infarction. Eur J Heart Fail. 2020; 22(4): 664–672.
  21. Byrne AB, Rossello X, Coughlan JJ, et al. 2023 ESC Guidelines for the management of acute coronary syndromes. Eur Heart J. 2023; 44(38): 3720–3826.
  22. Lawton JS, Tamis-Holland JE, Bangalore S, et al. 2021 ACC/AHA/SCAI Guideline for coronary artery revascularization: executive summary: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. Circulation 2022 18. 2022; 145(3): e4–e17.
  23. Webb JG, Lowe AM, Sanborn TA, et al. SHOCK Investigators. Percutaneous coronary intervention for cardiogenic shock in the SHOCK trial. J Am Coll Cardiol. 2003; 42(8): 1380–1386.
  24. Chiu FC, Chang SN, Lin JW, et al. Coronary artery bypass graft surgery provides better survival in patients with acute coronary syndrome or ST-segment elevation myocardial infarction experiencing cardiogenic shock after percutaneous coronary intervention: a propensity score analysis. J Thorac Cardiovasc Surg. 2009; 138(6): 1326–1330.
  25. Smilowitz NR, Alviar CL, Katz SD, et al. Coronary artery bypass grafting versus percutaneous coronary intervention for myocardial infarction complicated by cardiogenic shock. Am Heart J. 2020; 226: 255–263.
  26. McRae K, de Perrot M. Principles and indications of extracorporeal life support in general thoracic surgery. J Thorac Dis. 2018; 10(Suppl 8): S931–S946.