open access

Vol 15, No 1 (2021)
Case report
Published online: 2021-01-11
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Anoxic brain injury due to global ischemia: analysis of three clinical cases

Mikhail Kanarsky, Julia Nekrasova, Dmitriy Yankevich, Ekaterina Bondar, Margarita Radutnaya, Igor Znamensky, Anton Kudryavtsev, Ilya Borisov, Pranil Pradhan, Maria Miroshnichenko, Victoria Endler, Kirill Cherkashin
DOI: 10.5603/PMPI.2021.0001
·
Palliat Med Pract 2021;15(1):84-92.

open access

Vol 15, No 1 (2021)
Case report
Published online: 2021-01-11

Abstract

The article analyses three clinical cases of patients in a permanent vegetative state due to cardiac arrest
and prolonged cardiopulmonary resuscitation. All patients were admitted to Federal State Budget Scientific
Institution — Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow,
Russia. For diagnosing and prognosis for the progression of the disease a detailed examination was held,
including electroencephalography, polysomnography, positron emission computed tomography, singlephoton
emission computed tomography, functional perfusion computed tomography, electroneuromyography,
evoked potentials studies, laboratory studies, and other available tests. Instrumental diagnostics
methods confirm the principal component that determines the level of consciousness in this type of
damage — diffuse damage to the cerebral cortex. To conclude realization of the rehabilitation potential
of such patients is impossible without the control of nutritional support. Amino acid profile is one of the
markers and ways to control metabolic function.

Abstract

The article analyses three clinical cases of patients in a permanent vegetative state due to cardiac arrest
and prolonged cardiopulmonary resuscitation. All patients were admitted to Federal State Budget Scientific
Institution — Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow,
Russia. For diagnosing and prognosis for the progression of the disease a detailed examination was held,
including electroencephalography, polysomnography, positron emission computed tomography, singlephoton
emission computed tomography, functional perfusion computed tomography, electroneuromyography,
evoked potentials studies, laboratory studies, and other available tests. Instrumental diagnostics
methods confirm the principal component that determines the level of consciousness in this type of
damage — diffuse damage to the cerebral cortex. To conclude realization of the rehabilitation potential
of such patients is impossible without the control of nutritional support. Amino acid profile is one of the
markers and ways to control metabolic function.

Get Citation

Keywords

disorders of consciousness, global ischemia, amino acid profile, rehabilitation potential, melatonin

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About this article
Title

Anoxic brain injury due to global ischemia: analysis of three clinical cases

Journal

Palliative Medicine in Practice

Issue

Vol 15, No 1 (2021)

Article type

Case report

Pages

84-92

Published online

2021-01-11

DOI

10.5603/PMPI.2021.0001

Bibliographic record

Palliat Med Pract 2021;15(1):84-92.

Keywords

disorders of consciousness
global ischemia
amino acid profile
rehabilitation potential
melatonin

Authors

Mikhail Kanarsky
Julia Nekrasova
Dmitriy Yankevich
Ekaterina Bondar
Margarita Radutnaya
Igor Znamensky
Anton Kudryavtsev
Ilya Borisov
Pranil Pradhan
Maria Miroshnichenko
Victoria Endler
Kirill Cherkashin

References (14)
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