open access

Vol 15, No 1 (2021)
Case report
Published online: 2021-01-11
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Palliative surgery in a patient diagnosed with trisomy 18 and rare neurological comorbidities

Paula Szenejko, Stefan Anzelewicz, Piotr Czauderna
DOI: 10.5603/PMPI.2021.0003
·
Palliat Med Pract 2021;15(1):76-79.

open access

Vol 15, No 1 (2021)
Case report
Published online: 2021-01-11

Abstract

Introduction: The authors describe a case of a patient with a prenatal diagnosis of Trisomy 18 with atypical
manifestation, rare anomalies of the central nervous system and subsequent surgical treatment.
Case presentation: The infant was diagnosed with holoprosencephalia, schizencephalia, corpus callosum
agenesis and severe hydrocephalus. No significant heart, gastrointestinal or kidney defects were found.
Being in otherwise good condition, the patient was qualified for a ventriculi-peritoneal shunt surgery due
to rapidly increasing head circumference. Following the uneventful operation patient’s parents reported
a general improvement in their child condition.
Conclusions: Bearing in mind the possibility of complications and the child’s poor prognosis, the reasons
for surgical intervention were evaluated, as well as the possible outcomes of withholding invasive treatment.
Discussion over the benefits of palliative surgery and the risk of ‘palliative harm’ illustrate how selected
children benefit from an interventionist approach.

Abstract

Introduction: The authors describe a case of a patient with a prenatal diagnosis of Trisomy 18 with atypical
manifestation, rare anomalies of the central nervous system and subsequent surgical treatment.
Case presentation: The infant was diagnosed with holoprosencephalia, schizencephalia, corpus callosum
agenesis and severe hydrocephalus. No significant heart, gastrointestinal or kidney defects were found.
Being in otherwise good condition, the patient was qualified for a ventriculi-peritoneal shunt surgery due
to rapidly increasing head circumference. Following the uneventful operation patient’s parents reported
a general improvement in their child condition.
Conclusions: Bearing in mind the possibility of complications and the child’s poor prognosis, the reasons
for surgical intervention were evaluated, as well as the possible outcomes of withholding invasive treatment.
Discussion over the benefits of palliative surgery and the risk of ‘palliative harm’ illustrate how selected
children benefit from an interventionist approach.

Get Citation

Keywords

trisomy 18, Edwards syndrome, hydrocephalus, schizencephaly, holoprosencephalia, palliative surgery

About this article
Title

Palliative surgery in a patient diagnosed with trisomy 18 and rare neurological comorbidities

Journal

Palliative Medicine in Practice

Issue

Vol 15, No 1 (2021)

Article type

Case report

Pages

76-79

Published online

2021-01-11

DOI

10.5603/PMPI.2021.0003

Bibliographic record

Palliat Med Pract 2021;15(1):76-79.

Keywords

trisomy 18
Edwards syndrome
hydrocephalus
schizencephaly
holoprosencephalia
palliative surgery

Authors

Paula Szenejko
Stefan Anzelewicz
Piotr Czauderna

References (13)
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