Vol 13, No 4 (2019)
Review paper
Published online: 2020-01-03

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Opioids in clinical practice

Iwona Zaporowska-Stachowiak12, Mary-Tiffany Adannia Oduah3, Magdalena Celichowska4, Gabriela Dziuba4, Anna Mikołajczak4, Maria Perlińska4, Martyna Woźniak4, Lidia Gorzelinska2, Maciej Sopata2
Palliat Med Pract 2019;13(4):221-228.

Abstract

The treatment of pain improves quality of life. Opioids are commonly prescribed painkillers. The side effects
of opioids depend on the route of administration, dosage, drug metabolism, comorbid diseases and the
patient’s general condition. Despite many beneficial effects, opioids can lead to increased mortality in heart
failure, myocardial infarction, pulmonary oedema, and COPD. This article reviews specific uses of opioid
medications. Opioids induce immunosuppression, and may undergo drug-drug interactions, especially
during polytherapy or polypragmasia.

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