open access

Vol 6 (2021): Continuous Publishing
Case report
Published online: 2021-12-30
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Retinal nerve fiber layer defects in the presence of a physiological cup to disc ratio — a case series

Carlos Eduardo Rivera1234, Juan Carlos Aristizabal12, Edgar Muñoz51, Ankur Seth136
·
Ophthalmol J 2021;6:258-264.
Affiliations
  1. Collective Innovations Colombia, Cali, Colombia
  2. Pontificia Universidad Javeriana, Cali, Colombia
  3. GSR Medical Center, Cali, Colombia
  4. GSR International, United States
  5. UT Health San Antonio, San Antonio, United States
  6. University of Tennessee Health Science Center

open access

Vol 6 (2021): Continuous Publishing
CASE REPORTS
Published online: 2021-12-30

Abstract

Retinal nerve fiber layer (RNFL) defects are one of the earliest signs of glaucoma. Typically, these RNFL defects are associated with an increased cup/disc ratio and a thinning of the neuroretinal rim. When the cup/disc ratio is within normal limits, the observer can misdiagnose subtle RNFL defects and lead to an essential delay in diagnosis, which has negative visual consequences in these patients. We present a case series report addressing RNFL defects with a physiological cup/disc ratio.

Abstract

Retinal nerve fiber layer (RNFL) defects are one of the earliest signs of glaucoma. Typically, these RNFL defects are associated with an increased cup/disc ratio and a thinning of the neuroretinal rim. When the cup/disc ratio is within normal limits, the observer can misdiagnose subtle RNFL defects and lead to an essential delay in diagnosis, which has negative visual consequences in these patients. We present a case series report addressing RNFL defects with a physiological cup/disc ratio.

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Keywords

glaucoma; retinal nerve fiber defects; cup/disc ratio

About this article
Title

Retinal nerve fiber layer defects in the presence of a physiological cup to disc ratio — a case series

Journal

Ophthalmology Journal

Issue

Vol 6 (2021): Continuous Publishing

Article type

Case report

Pages

258-264

Published online

2021-12-30

Page views

5712

Article views/downloads

595

DOI

10.5603/OJ.2021.0043

Bibliographic record

Ophthalmol J 2021;6:258-264.

Keywords

glaucoma
retinal nerve fiber defects
cup/disc ratio

Authors

Carlos Eduardo Rivera
Juan Carlos Aristizabal
Edgar Muñoz
Ankur Seth

References (13)
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  10. Tuulonen A, Lehtola J, Airaksinen P. Nerve Fiber Layer Defects with Normal Visual Fields. Ophthalmology. 1993; 100(5): 587–598.
  11. Jonas JB, Schiro D. Localized retinal nerve fiber layer defects in nonglaucomatous optic nerve atrophy. Graefes Arch Clin Exp Ophthalmol. 1994; 232(12): 759–760.
  12. Hwang YH, Kim YY, Kim HKi, et al. Ability of cirrus high-definition spectral-domain optical coherence tomography clock-hour, deviation, and thickness maps in detecting photographic retinal nerve fiber layer abnormalities. Ophthalmology. 2013; 120(7): 1380–1387.
  13. Foster PJ, Buhrmann R, Quigley HA, et al. The definition and classification of glaucoma in prevalence surveys. Br J Ophthalmol. 2002; 86(2): 238–242.

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