Vol 5 (2020): Continuous Publishing
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Published online: 2020-02-06

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Risk factors associated with development of senile cataract

Pragati Garg1, Ritika Mullick1, Bharti Nigam1, Priyanka Raj1
Ophthalmol J 2020;5:17-24.


Background: Cataract is the most common cause of reversible blindness worldwide, which has been associated with various causative risk factors. Hence, we aim to study the factors that might play a role in cataractogenesis.

Material and methods: A total of 240 eyes of 240 subjects were included for the study, which consisted of 120 cases with age-related cataract and 120 age-matched controls, and in them various factors like blood pressure, body mass index (BMI), smoking, sun exposure, and serum cholesterol were studied.

Results: A statistically significant difference between the two groups was found with respect to smoking profile (p = 0.007), sun exposure (p = 0.001), and serum cholesterol (p < 0.001). Subjects who were smokers, had a longer exposure to sun, and had higher serum cholesterol level were found to be positively associated with development of cataract. No significant association between BMI (p = 0.384) and blood pressure (p > 0.05) was observed.

Conclusion: Higher cholesterol levels, increased sun exposure, and smoking habit play a role in the development of senile cataract, and these are modifiable risk factors. Hence, control of these might help in delaying formation and progression of cataract.

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