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Assessment of retinal and optic disc vascular perfusion density in retinitis pigmentosa patients by optical coherence tomography angiography
Affiliations- Department of Surgery/Ophthalmology, King Hussein Cancer Center (KHCC), Amman, Jordan
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Abstract
Background: The aim of the study was to evaluate the vascular flow density measured by optical coherence tomography angiography in patients with retinitis pigmentosa and to compare it with normal subjects. Material and methods: This was a cross-sectional case control study employing 16 eyes of eight patients with retinitis pigmentosa and 16 eyes of eight healthy subjects. Optical coherence tomography angiography was performed in all subjects. The macula was imaged with a 3 × 3 mm scan, whereas for the optic nerve head, a 4.5 × 4.5 mm scan was taken. Macular and optic disc vascular flow perfusion densities were measured. In addition, the FAZ area was calculated. All data were compared in the two groups. Results: The vascular flow perfusion density in the macular and in the optic nerve head was significantly lower in the retinitis pigmentosa group when compared with the control group. On the other hand, the foveal avascular zones area was not significantly different from controls. Conclusion: Patients with retinitis pigmentosa show a decreased macular and optic nerve head perfusion density compared with healthy subjects
Abstract
Background: The aim of the study was to evaluate the vascular flow density measured by optical coherence tomography angiography in patients with retinitis pigmentosa and to compare it with normal subjects. Material and methods: This was a cross-sectional case control study employing 16 eyes of eight patients with retinitis pigmentosa and 16 eyes of eight healthy subjects. Optical coherence tomography angiography was performed in all subjects. The macula was imaged with a 3 × 3 mm scan, whereas for the optic nerve head, a 4.5 × 4.5 mm scan was taken. Macular and optic disc vascular flow perfusion densities were measured. In addition, the FAZ area was calculated. All data were compared in the two groups. Results: The vascular flow perfusion density in the macular and in the optic nerve head was significantly lower in the retinitis pigmentosa group when compared with the control group. On the other hand, the foveal avascular zones area was not significantly different from controls. Conclusion: Patients with retinitis pigmentosa show a decreased macular and optic nerve head perfusion density compared with healthy subjects
Keywords
retinitis pigmentosa; OCTA; angiography; OCT; optical coherence tomography
About this articleTitle
Assessment of retinal and optic disc vascular perfusion density in retinitis pigmentosa patients by optical coherence tomography angiography
Journal
Issue
Vol 4 (2019): Continuous Publishing
Article type
Original paper
Pages
100-104
Published online
2019-12-06
Page views
775
Article views/downloads
649
DOI
Bibliographic record
Ophthalmol J 2019;4:100-104.
Keywords
retinitis pigmentosa
OCTA
angiography
OCT
optical coherence tomography
Authors
Katarzyna Baltaziak
Lucyna Baltaziak
Rashed Mustafa Nazzal
Anna Woźniak
Robert Rejdak
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