open access

Vol 4 (2019): Continuous Publishing
CASE REPORTS
Published online: 2019-07-31
Get Citation

Holmes-Adie syndrome

Zubaida Sirang, Irfan Jeeva
DOI: 10.5603/OJ.2019.0008
·
Ophthalmol J 2019;4:44-45.

open access

Vol 4 (2019): Continuous Publishing
CASE REPORTS
Published online: 2019-07-31

Abstract

Holmes-Adie syndrome (HAS) is a rare neuro-ophthalmological disorder, which mostly presents in young females
as a unilateral dilated pupil. We present a case of a 12-year-old girl with bilateral tonic pupils. She had vermiform
movement of the iris with segmental palsy, as well as loss of ankle jerks. The diagnosis was confirmed with pilocarpine
0.125% test, and she was symptomatically treated with the same drops.

Abstract

Holmes-Adie syndrome (HAS) is a rare neuro-ophthalmological disorder, which mostly presents in young females
as a unilateral dilated pupil. We present a case of a 12-year-old girl with bilateral tonic pupils. She had vermiform
movement of the iris with segmental palsy, as well as loss of ankle jerks. The diagnosis was confirmed with pilocarpine
0.125% test, and she was symptomatically treated with the same drops.

Get Citation

Keywords

Holmes-Adie syndrome; tonic pupils; light-near dissociation

About this article
Title

Holmes-Adie syndrome

Journal

Ophthalmology Journal

Issue

Vol 4 (2019): Continuous Publishing

Pages

44-45

Published online

2019-07-31

DOI

10.5603/OJ.2019.0008

Bibliographic record

Ophthalmol J 2019;4:44-45.

Keywords

Holmes-Adie syndrome
tonic pupils
light-near dissociation

Authors

Zubaida Sirang
Irfan Jeeva

References (11)
  1. Adie WJ. Tonic pupils and absent tendon reflexes: a benign disorder sui generis; its complete and incomplete forms. Brain. 1932; 55(1): 98–113.
  2. Martinelli P. Holmes-Adie syndrome. The Lancet. 2000; 356(9243): 1760–1761.
  3. Guaraldi P, Mathias CJ. Progression of cardiovascular autonomic dysfunction in Holmes-Adie syndrome. J Neurol Neurosurg Psychiatry. 2011; 82(9): 1046–1049.
  4. Siddiqui AA, Clarke JC, Grzybowski A. William John Adie: the man behind the syndrome. Clin Exp Ophthalmol. 2014; 42(8): 778–784.
  5. Bremner FD, Smith SE. Bilateral tonic pupils: Holmes Adie syndrome or generalised neuropathy? Br J Ophthalmol. 2007; 91(12): 1620–1623.
  6. Thompson HS, Kardon RH. The Argyll Robertson Pupil. J Neuroophthalmol. 2006; 26(2): 134–138.
  7. Bilateral tonic pupils: Holmes-Adie syndrome or generalised neuropathy? Br J Ophthalmol. 2007; 91(12): 1620–1623.
  8. Thompson HS. Adie's syndrome: some new observations. Trans Am Ophthalmol Soc. 1977; 75: 587–626.
  9. Moeller JJ, Maxner CE. The dilated pupil: an update. Curr Neurol Neurosci Rep. 2007; 7(5): 417–422.
  10. Mayer H. Bilateral tonic pupils secondary to Ross syndrome: a case report. J Optom. 2014; 7(2): 106–107.
  11. Csak T, Folhoffer A, Horvath A, et al. Holmes-Adie syndrome, autoimmune hepatitis and celiac disease: a case report. World J Gastroenterol. 2006; 12(9): 1485–1487.

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

VM Media sp. z o.o. VM Group sp.k., Grupa Via Medica, 73 Świętokrzyska St., 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl