open access
Retinoma — the first identified case in Jordan
Affiliations- Department of Surgery/Ophthalmology, King Hussein Cancer Center (KHCC), Amman, Jordan
- King Hussein Cancer Center, Amman, Jordan
open access
Abstract
Retinoma (or retinocytoma) is a rare benign intraocular tumor with characteristic features and can be diagnosed clinically. In this article, we present a case report and a review of literature about retinoma. The case is about an incidentally diagnosed retinoma in an asymptomatic young female who presented for vision checkup and was found to have an intraocular translucent-grey, elevated mass extending into the vitreous cavity from the retina with the characteristic features of retinoma. The main differential diagnosis included retinoblastoma and astrocytic hamartoma. The mass showed no growth over a period of 6 months of follow up with colored fundus photography and ultrasound. This case is, to the best of our knowledge, the first case of retinoma diagnosed in Jordan.
Abstract
Retinoma (or retinocytoma) is a rare benign intraocular tumor with characteristic features and can be diagnosed clinically. In this article, we present a case report and a review of literature about retinoma. The case is about an incidentally diagnosed retinoma in an asymptomatic young female who presented for vision checkup and was found to have an intraocular translucent-grey, elevated mass extending into the vitreous cavity from the retina with the characteristic features of retinoma. The main differential diagnosis included retinoblastoma and astrocytic hamartoma. The mass showed no growth over a period of 6 months of follow up with colored fundus photography and ultrasound. This case is, to the best of our knowledge, the first case of retinoma diagnosed in Jordan.
Keywords
retinoma; retinocytoma; retinoblastoma; Jordan
About this articleTitle
Retinoma — the first identified case in Jordan
Journal
Issue
Vol 4 (2019): Continuous Publishing
Article type
Case report
Pages
52-55
Published online
2019-07-31
Page views
870
Article views/downloads
958
DOI
Bibliographic record
Ophthalmol J 2019;4:52-55.
Keywords
retinoma
retinocytoma
retinoblastoma
Jordan
Authors
Rashed Mustafa Nazzal
Yacoub Yousef
Katarzyna Nowomiejska
Robert Rejdak
References (16)- Gallie BL, Ellsworth RM, Abramson DH, et al. Retinoma: spontaneous regression of retinoblastoma or benign manifestation of the mutation? Br J Cancer. 1982; 45(4): 513–521.
- Sampieri K, Mencarelli MA, Epistolato MC, et al. Genomic differences between retinoma and retinoblastoma. Acta Oncol. 2008; 47(8): 1483–1492.
- Eagle RC, Shields JA, Donoso L, et al. Malignant transformation of spontaneously regressed retinoblastoma, retinoma/retinocytoma variant. Ophthalmology. 1989; 96(9): 1389–1395.
- Margo C, Hidayat A, Kopelman J, et al. Retinocytoma. A benign variant of retinoblastoma. Arch Ophthalmol. 1983; 101(10): 1519–1531.
- Balmer A, Munier F, Gailloud C. Retinoma. Case studies. Ophthalmic Paediatr Genet. 1991; 12(3): 131–137.
- Singh AD, Santos CM, Shields CL, et al. Observations on 17 patients with retinocytoma. Arch Ophthalmol. 2000; 118(2): 199–205.
- Dimaras H, Khetan V, Halliday W, et al. Loss of RB1 induces non-proliferative retinoma: increasing genomic instability correlates with progression to retinoblastoma. Hum Mol Genet. 2008; 17(10): 1363–1372.
- Lommatzsch PK, Zimmermann W, Lommatzsch R. [Spontaneous growth inhibition in retinoblastoma]. Klin Monbl Augenheilkd. 1993; 202(3): 218–223.
- Hadjistilianou T, De Francesco S, Martone G, et al. Retinocytoma associated with calcified vitreous deposits. Eur J Ophthalmol. 2006; 16(2): 349–351.
- Abouzeid H, Balmer A, Moulin AP, et al. Phenotypic variability of retinocytomas: preregression and postregression growth patterns. Br J Ophthalmol. 2012; 96(6): 884–889.
- Shah PK, Narendran V, Manayath GJ, et al. Atypical retinocytoma with diffuse vitreous seeds: An insight. Oman J Ophthalmol. 2011; 4(2): 81–83.
- Yousef YA, Nazzal RM, Khalil MB, et al. Management outcome(s) in eyes with retinoblastoma previously inadequately treated with systemic chemotherapy alone without focal therapy. Oman J Ophthalmol. 2017; 10(2): 70–75.
- Yousef Y, Mahameed I. External Beam Radiation Therapy for Retinoblastoma Resistant to Chemotherapy and Focal Treatment: Outcome and Predictive Factors. J Clin Exp Oncol. 2015; 04(02): 2–6.
- Abramson DH. Retinoma, retinocytoma, and the retinoblastoma gene. Arch Ophthalmol. 1983; 101(10): 1517–1518.
- Gallie BL, Dunn JM, Chan HS, et al. The genetics of retinoblastoma. Relevance to the patient. Pediatr Clin North Am. 1991; 38(2): 299–315.
- Jaradat I, Yousef YA, Mehyar M, et al. Retinoblastoma in Jordan: an epidemiological study (2006-2010). Hematol Oncol Stem Cell Ther. 2011; 4(3): 126–131.