Refractory macular edema in X-linked juvenile retinoschisis
Abstract
X-linked juvenile retinoschisis (XLRS) is one of the most common X-linked inherited, bilateral vitreoretinal dystrophies
affecting males in the first two decades of life. In this article, we present a case report of a young man who
presented with gradual decrease in visual acuity in both eyes that was attributed to macular edema and foveal schisis
in the inner retinal layers. He was investigated by appropriate ocular images which were consistent with a diagnosis
of XLRS. He was treated by anti-vascular endothelial growth factor (anti-VEGF) intravitreal injection, dorzolamide
eye drops and intravitreal steroids injection without improvement.
Keywords: retinoschisismacular edemajuvenilecarbonic anhydrase inhibitorsvascular endothelial growth factor
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