Vol 9 (2024): Continuous Publishing
Case report
Published online: 2024-04-29

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Bacillary layer setachment (BALAD) in neovascular age-related macular degeneration — three years’ follow-up of a case study

Małgorzata Latalska1, Anna Matysik-Woźniak1, Luca di Antonio2
Ophthalmol J 2024;9:77-81.


The study aimed to present a case of bacillary layer detachment (BALAD) in a patient with neovascular age-related macular degeneration (nAMD) treated with brolucizumab.

An 85-year-old patient with nAMD underwent a comprehensive clinical examination and multimodal imaging
analysis. The patient received a series of injections with initial retinal layers and visual acuity (BCVA) improvements. After five injections, there were notable improvements in the retinal appearance and BCVA (enhanced from 1.3 to 0.22 logMAR). However, it later decreased to 1.0 logMAR due to the development of fibrosis and ellipsoid zone (EZ) disruption.

The study highlights the resolution of BALAD after the initial brolucizumab treatment but also emphasizes the difficulties in handling nAMD. Later fibrotic changes and disruptions in the EZ negatively impacted the long-term visual outcome.

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