Vol 9 (2024): Continuous Publishing
Case report
Published online: 2024-06-28

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Binocular vision disorders and tear meniscus parameters using anterior segment-optical coherence tomography (AS-OCT) in Parkinson’s disease: a case report

Pritam Dutta1
Ophthalmol J 2024;9:100-105.

Abstract

BACKGROUND: Ocular abnormalities are potential consequences of early signs of Parkinson’s disease (PD). The novelty of this case is that it provides additional binocular vision findings for better diagnosis and demonstrates the role of imaging techniques such as anterior segment-optical coherence tomography (AS-OCT) to quantitatively assess the ocular surface in PD.

CASE PRESENTATION: A 55-year-old male with early Parkinson’s disease presented with a history of transient diplopia, irritation, and burning sensation one year after his PD diagnosis. On examination, his contrast sensitivity was reduced, and he had receded convergence amplitude, poor saccadic function, and reduced developmental eye movement (DEM) test. Additionally, his tear meniscus parameters were significantly reduced when measured quantitatively.

CONCLUSION: Convergence insufficiency and eye movement deficit may serve as early oculomotor signs of PD. Imaging techniques such as AS-OCT, which quantitatively assess the ocular surface, could also serve as diagnostic tools in the early detection of underlying symptoms associated with dry eyes.

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References

  1. Antal A, Bandini F, Kéri S, et al. Visuo-cognitive dysfunctions in Parkinson's disease. Clin Neurosci. 1998; 5(2): 147–152.
  2. Davidsdottir S, Cronin-Golomb A, Lee A. Visual and spatial symptoms in Parkinson's disease. Vision Res. 2005; 45(10): 1285–1296.
  3. Scheiman M, Wick B. Clinical management of binocular vision: Heterophoric, accommodative, and eye movement disorders. 4th ed. Wolters Kluwer Health 2023: 3–52.
  4. Maples WC. NSUCO oculomotor test. Optometric Extension Program, Santa Ana, CA 1995.
  5. Garzia RP, Richman JE, Nicholson SB, et al. A new visual-verbal saccade test: the development eye movement test (DEM). J Am Optom Assoc. 1990; 61: 124–35.
  6. Grubbs JR, Tolleson-Rinehart S, Huynh K, et al. A review of quality of life measures in dry eye questionnaires. Cornea. 2014; 33(2): 215–218.
  7. Tomsak RL, Daroff RB. Ophthalmologic features of Parkinson's disease. Neurology. 2004; 63(5): 940–1; author reply 940.
  8. Hanuška J, Bonnet C, Rusz J, et al. Fast vergence eye movements are disrupted in Parkinson's disease: A video-oculography study. Parkinsonism Relat Disord. 2015; 21(7): 797–799.
  9. Anang JBM, Gagnon JF, Bertrand JA, et al. Predictors of dementia in Parkinson disease: a prospective cohort study. Neurology. 2014; 83(14): 1253–1260.
  10. Matsumoto H, Terao Y, Furubayashi T, et al. Small saccades restrict visual scanning area in Parkinson's disease. Mov Disord. 2011; 26(9): 1619–1626.
  11. Terao Y, Fukuda H, Ugawa Y, et al. New perspectives on the pathophysiology of Parkinson's disease as assessed by saccade performance: a clinical review. Clin Neurophysiol. 2013; 124(8): 1491–1506.
  12. Dutta P. Oculomotor Dysfunction in Parkinson’s Disease. Eur J Geriatr Gerontol. 2020; 2(3): 87–89.
  13. Tamer C, Melek IM, Duman T, et al. Tear film tests in Parkinson's disease patients. Ophthalmology. 2005; 112(10): 1795.
  14. Kandel ER, Schwartz J, Jessel TM. ed. Principles of Neural Science. 3rd ed. Elsevier, New York 1991.
  15. Yuan Y, Wang J, Chen Qi, et al. Reduced tear meniscus dynamics in dry eye patients with aqueous tear deficiency. Am J Ophthalmol. 2010; 149(6): 932–938.e1.
  16. Palakuru JR, Wang J, Aquavella JV. Effect of blinking on tear dynamics. Invest Ophthalmol Vis Sci. 2007; 48(7): 3032–3037.
  17. Raj A, Dhasmana R, Nagpal RC. Anterior Segment Optical Coherence Tomography for Tear Meniscus Evaluation and its Correlation with other Tear Variables in Healthy Individuals. J Clin Diagn Res. 2016; 10(5): NC01–NC04.