open access

Vol 8 (2023): Continuous Publishing
Case report
Published online: 2023-11-28
Get Citation

Bilateral uveal tumor — a case report

Karolina Bonińska12, Sławomir Lis2, Marzena Szczepaniak2, Sławomir Cisiecki12
·
Ophthalmol J 2023;8:138-141.
Affiliations
  1. Ophthalmology Department, Karol Jonscher Municipal Medical Center in Lodz, Poland
  2. Medical Center “Julianów” in Lodz, Poland

open access

Vol 8 (2023): Continuous Publishing
CASE REPORTS
Published online: 2023-11-28

Abstract

BACKGROUND: This case presentation reports a case of bilateral uveal tumor.

CASE PRESENTATION: An 82-year-old patient reported to the ophthalmology department complaining of a limited visual field temporally in his left eye. Visual acuity in the right eye was 0.9, and in the left eye, it was 0.4. Intraocular pressure was 18 mm Hg in each eye. Indirect ophthalmoscopy in the left eye revealed a choroidal tumor. The diagnosis of uveal melanoma was confirmed, and the patient underwent a 125I brachytherapy procedure. During a follow-up visit, a tumor was observed to be spreading beyond the left eyeball, with evidence of metastatic deposits observed on the corneal endothelium. The patient underwent enucleation surgery. Two years later, the patient reported to our Ophthalmology Clinic with a significant deterioration of visual acuity in the right eye (0.2); intraocular pressure was 8 mm Hg. Indirect ophthalmoscopy revealed a choroidal tumor with subretinal fluid.

CONCLUSION: The location of bilateral choroidal melanoma should always be considered. It becomes crucial to carefully and regularly examine both eyes when uveal melanoma is found in one eye. The result of the examination may determine the type of treatment undertaken and, thus the prognosis for long-term survival.

 

Abstract

BACKGROUND: This case presentation reports a case of bilateral uveal tumor.

CASE PRESENTATION: An 82-year-old patient reported to the ophthalmology department complaining of a limited visual field temporally in his left eye. Visual acuity in the right eye was 0.9, and in the left eye, it was 0.4. Intraocular pressure was 18 mm Hg in each eye. Indirect ophthalmoscopy in the left eye revealed a choroidal tumor. The diagnosis of uveal melanoma was confirmed, and the patient underwent a 125I brachytherapy procedure. During a follow-up visit, a tumor was observed to be spreading beyond the left eyeball, with evidence of metastatic deposits observed on the corneal endothelium. The patient underwent enucleation surgery. Two years later, the patient reported to our Ophthalmology Clinic with a significant deterioration of visual acuity in the right eye (0.2); intraocular pressure was 8 mm Hg. Indirect ophthalmoscopy revealed a choroidal tumor with subretinal fluid.

CONCLUSION: The location of bilateral choroidal melanoma should always be considered. It becomes crucial to carefully and regularly examine both eyes when uveal melanoma is found in one eye. The result of the examination may determine the type of treatment undertaken and, thus the prognosis for long-term survival.

 

Get Citation

Keywords

uveal melanoma; bilateral tumor

About this article
Title

Bilateral uveal tumor — a case report

Journal

Ophthalmology Journal

Issue

Vol 8 (2023): Continuous Publishing

Article type

Case report

Pages

138-141

Published online

2023-11-28

Page views

309

Article views/downloads

120

DOI

10.5603/oj.94017

Bibliographic record

Ophthalmol J 2023;8:138-141.

Keywords

uveal melanoma
bilateral tumor

Authors

Karolina Bonińska
Sławomir Lis
Marzena Szczepaniak
Sławomir Cisiecki

References (17)
  1. McLaughlin CC, Wu XC, Jemal A, et al. Incidence of noncutaneous melanomas in the U.S. Cancer. 2005; 103(5): 1000–1007.
  2. Singh AD, Topham A, Singh AD, et al. Incidence of uveal melanoma in the United States: 1973-1997. Ophthalmology. 2003; 110(5): 956–961.
  3. Damato B. Progress in the management of patients with uveal melanoma. The 2012 Ashton Lecture. Eye (Lond). 2012; 26(9): 1157–1172.
  4. Scott JF, Vyas R, Galvin J, et al. Primary bilateral uveal melanoma: a population-based study and systematic review. Clin Exp Ophthalmol. 2018; 46(5): 502–510.
  5. Eide N, Garred Ø, Beiske K, et al. Bilateral uveal melanomas with different gene expression detected with 7 years interval. Acta Ophthalmol. 2016; 94(1): 99–102.
  6. Shields CL, Kaliki S, Furuta M, et al. Clinical spectrum and prognosis of uveal melanoma based on age at presentation in 8,033 cases. Retina. 2012; 32(7): 1363–1372.
  7. Rai K, Pilarski R, Cebulla CM, et al. Comprehensive review of BAP1 tumor predisposition syndrome with report of two new cases. Clin Genet. 2016; 89(3): 285–294.
  8. Żygulska-Mach H. Epidemiology. In: Skowronek J, Mackiewicz A. ed. Czerniak złośliwy. Termedia, Poznan 1998: 145–149.
  9. Becker JC, Terheyden P, Kämpgen E, et al. Treatment of disseminated ocular melanoma with sequential fotemustine, interferon α, and interleukin 2. Br J Cancer. 2002; 87(8): 840–845.
  10. Camp R, Lind DS, Hemming AW. Combined liver and pancreas resection with biochemiother- apy for metastatic ocular melanoma. J Hepatobiliary Pancreat Surg. 2002; 9(4): 519–521.
  11. Zygulska-Mach H. [Modern treatment of malignant intraocular melanomas]. Klin Oczna. 1996; 98(1): 61–66.
  12. Alexander HR, Libutti SK, Bartlett DL, et al. A phase I-II study of isolated hepatic perfusion using melphalan with or without tumor necrosis factor for patients with ocular melanoma metastatic to liver. Clin Cancer Res. 2000; 6(8): 3062–3070.
  13. Kulik A, Olszewska A, Bulski W, et al. Brachytherapy in the conservative treatment of malignant intraocular melanomas. Cancer. 1998; 48: 1077–1088.
  14. Stankiewicz A, Figurska M. Melanoma of the eye. Co Oncol. 2003; 7: 589–593.
  15. Weinreich DM, Alexander HR. Transarterial perfusion of liver metastases. Semin Oncol. 2002; 29(2): 136–144.
  16. Biedka M, Makarewicz R. Liver metastases in patients with ocular melanoma. Pol Palliat Med. 2005; 4(2).
  17. Romanowska-Dixon B, Jakubowska B. Melanoma of the Vascular Membrane. Differential diagnosis of intraocular neoplasms. Krakow 2014.

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Publisher: VM Media Group sp. z o.o., Grupa Via Medica, 73 Świętokrzyska St., 80–180 Gdańsk

tel.:+48 58 310 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl