Vol 6 (2021): Continuous Publishing
Case report
Published online: 2021-12-30

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Optical coherence tomography findings in compressive optic neuropathy and pre-existing glaucoma

Carlos Eduardo Rivera1234, Catalina Ferreira1234, Juan Carlos Aristizabal12, Edgar Muñoz15, Ankur Seth136
Ophthalmol J 2021;6:249-254.

Abstract

Background: We present the optical coherence tomography (OCT) findings in macular ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL) in a case of a female patient with craniopharyngioma and preexisting glaucoma.

Case presentation: 80-year-old female patient with a history of successfully suprasellar resection of craniopharyngioma performed eight years earlier and preexisting primary open-angle glaucoma treated with latanoprost indicated a one-month history of decreased vision in the left eye. The visual field showed a vertical hemifield defect in the right eye and an inferior arcuate defect in the left eye. A cerebral magnetic resonance image confirmed a new suprasellar tumor. The patient was successfully operated on one week after diagnosis. Visual acuity in her left eye improved substantially after surgery.

Results: Optical coherence tomography of macular and RNFL showed thinning in the patient’s right eye that corresponded with the vertical visual field defect. A “C” pattern that compromised the horizontal meridian differentiated from glaucoma that respects the horizontal meridian. The visual field showed a vertical hemifield defect in the right eye and an inferior arcuate defect in the left eye.

Conclusions: Optical coherence tomography is a non-invasive imaging procedure. It helps identify compression of the anterior visual pathways, resulting in progressive thinning of RNFL and macular ganglion cell complex (GCC). It has a good correlation with visual fields.

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References

  1. Hoyt WF, Luis O. The primate chiasm. Details of visual fiber organization studied by silver impregnation techniques. Arch Ophthalmol. 1963; 70: 69–85.
  2. Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science. 1991; 254(5035): 1178–1181.
  3. Popescu DP, Choo-Smith LP, Flueraru C, et al. Optical coherence tomography: fundamental principles, instrumental designs and biomedical applications. Biophys Rev. 2011; 3(3): 155.
  4. Micieli JA, Newman NJ, Biousse V. The role of optical coherence tomography in the evaluation of compressive optic neuropathies. Curr Opin Neurol. 2019; 32(1): 115–123.
  5. Bussel II, Wollstein G, Schuman JS. OCT for glaucoma diagnosis, screening and detection of glaucoma progression. Br J Ophthalmol. 2014; 98(Suppl 2): ii15–ii19.
  6. Al-Dahmani K, Mohammad S, Imran F, et al. Sellar Masses: An Epidemiological Study. Can J Neurol Sci. 2016; 43(2): 291–297.
  7. Biousse V, Newman N. Diagnosis and clinical features of common optic neuropathies. Lancet Neurol. 2016; 15(13): 1355–1367.
  8. Unsöld R, Hoyt WF. Band atrophy of the optic nerve. The histology of temporal hemianopsia. Arch Ophthalmol. 1980; 98(9): 1637–1638.
  9. Mwanza JC, Oakley JD, Budenz DL, et al. Cirrus Optical Coherence Tomography Normative Database Study Group. Ability of cirrus HD-OCT optic nerve head parameters to discriminate normal from glaucomatous eyes. Ophthalmology. 2011; 118(2): 241–248.e1.
  10. Sun M, Zhang Z, Ma C, et al. Quantitative analysis of retinal layers on three-dimensional spectral-domain optical coherence tomography for pituitary adenoma. PLoS One. 2017; 12(6): e0179532.
  11. Akashi A, Kanamori A, Ueda K, et al. The detection of macular analysis by SD-OCT for optic chiasmal compression neuropathy and nasotemporal overlap. Invest Ophthalmol Vis Sci. 2014; 55(7): 4667–4672.
  12. Zehnder S, Wildberger H, Hanson JVM, et al. Retinal Ganglion Cell Topography in Patients With Visual Pathway Pathology. J Neuroophthalmol. 2018; 38(2): 172–178.
  13. Monteiro MLR, Hokazono K, Fernandes DB, et al. Evaluation of inner retinal layers in eyes with temporal hemianopic visual loss from chiasmal compression using optical coherence tomography. Invest Ophthalmol Vis Sci. 2014; 55(5): 3328–3336.
  14. Tieger MG, Hedges TR, Ho J, et al. Ganglion Cell Complex Loss in Chiasmal Compression by Brain Tumors. J Neuroophthalmol. 2017; 37(1): 7–12.
  15. Newman S, Turbin R, Bodach M, et al. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Pretreatment Ophthalmology Evaluation in Patients With Suspected Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016; 79(4): E530–E532.
  16. Danesh-Meyer HV, Wong A, Papchenko T, et al. Optical coherence tomography predicts visual outcome for pituitary tumors. J Clin Neurosci. 2015; 22(7): 1098–1104.
  17. Moon CH, Hwang SC, Ohn YH, et al. The time course of visual field recovery and changes of retinal ganglion cells after optic chiasmal decompression. Invest Ophthalmol Vis Sci. 2011; 52(11): 7966–7973.
  18. Cottee L, Daniel C, Loh W, et al. Remyelination and recovery of conduction in cat optic nerve after demyelination by pressure. Exp Neurol. 2003; 184(2): 865–877.
  19. Danesh-Meyer HV, Papchenko T, Savino PJ, et al. In vivo retinal nerve fiber layer thickness measured by optical coherence tomography predicts visual recovery after surgery for parachiasmal tumors. Invest Ophthalmol Vis Sci. 2008; 49(5): 1879–1885.
  20. Yum HRi, Park SH, Park HYL, et al. Macular Ganglion Cell Analysis Determined by Cirrus HD Optical Coherence Tomography for Early Detecting Chiasmal Compression. PLoS One. 2016; 11(4): e0153064.