Tom 7, Nr 6 (2021)
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Opublikowany online: 2021-12-20

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Eksport do Mediów Społecznościowych

Eksport do Mediów Społecznościowych

Przyczyny BIA-ALCL — podsumowanie aktualnego stanu wiedzy

Agnieszka Ławnicka1, Sławomir Cieśla1, Piotr Pluta2, Aleksandra Przybylska3, Dawid Murawa14
Onkol Prakt Klin Edu 2021;7(6):402-408.

Streszczenie

Przyczyny rozwoju anaplastycznego chłoniaka wielkokomórkowego związanego z implantami piersi (BIA-ALCL) są ostatnio dość popularnym tematem, budzącym szczególne zainteresowanie chirurgów plastycznych, chirurgów onkologicznych, hematologów i onkologów. W ciągu ostatniej dekady ukazało się wiele publikacji na ten temat. Potencjalne czynniki etiopatogenetyczne obejmują rodzaj implantów, biofilm, obecność stanu zapalnego, mikrourazy i mutacje genetyczne. W stosunku do żadnej z tych potencjalnych przyczyn nie uzyskano jednak dotychczas wystarczających dowodów naukowych, w każdym razie nie należy ich rozpatrywać osobno, ponieważ prawdopodobnie występują one jednocześnie. Określenie głównego czynnika etiopatogenetycznego wymaga dalszych badań i wymiany doświadczeń między klinicystami i badaczami. Przyczyniłoby się to do poszerzenia możliwości zastosowania skutecznej profilaktyki u pacjentek poddawanych operacji wszczepienia implantów piersi, a być może nawet wyeliminowania BIA-ALCL.

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