Tom 7, Nr 5 (2021)
Artykuł przeglądowy
Opublikowany online: 2021-11-25
Chemioimmunoterapia drobnokomórkowego raka płuca w stadium rozsiewu
Onkol Prakt Klin Edu 2021;7(5):294-296.
Streszczenie
W artykule przedstawiono aktualny stan wiedzy dotyczący leczenia drobnokomórkowego raka płuca (DRP) w stadium rozsiewu z udziałem chemioterapii i immunoterapii.
Słowa kluczowe: drobnokomórkowy rak płucachemioterapiaimmunoterapiaatezolizumabdurwalumab
Referencje
- Mansfield AS, Każarnowicz A, Karaseva N, et al. IMpower133 Study Group. First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell Lung Cancer. N Engl J Med. 2018; 379(23): 2220–2229.
- Goldman JW, Dvorkin M, Chen Y, et al. CASPIAN investigators, CASPIAN investigators. Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial. Lancet. 2019; 394(10212): 1929–1939.
- Liu SV, Horn L, Mok T, et al. 1781MO IMpower133: Characterisation of long-term survivors treated first-line with chemotherapy ± atezolizumab in extensive-stage small cell lung cancer. Ann Oncol. 2020; 31: S1032–S1033.
- Paz-Ares L, Dvorkin M, Chen Y, et al. Durvalumab ± tremelimumab + platinum-etoposide in first-line extensive-stage SCLC (ES-SCLC): Updated results from the phase III CASPIAN study. J Clin Oncol. 2020; 38(15_suppl): 9002–9002.
- Goldman JW, Dvorkin M, Chen Y, et al. CASPIAN investigators. Durvalumab, with or without tremelimumab, plus platinum-etoposide versus platinum-etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated results from a randomised, controlled, open-label, phase 3 trial. Lancet Oncol. 2021; 22(1): 51–65.