Vol 6, No 6 (2010)
Guidelines / Expert consensus
Published online: 2011-02-24
Recommendations for diagnostics and therapy of adult patients with malignant primary bone tumors
Onkol. Prak. Klin 2010;6(6):355-369.
Abstract
Bone sarcomas comprise a heterogenous group of rare mesenchymal tumors (less than 0.5%
of malignant neoplasms in adults). From clinical point of view they can be divided into two main
groups: spindle-cell sarcomas (osteosarcomas, majority of chondrosarcomas and less common
subtypes) and small-cell sarcomas (mainly Ewing family of tumors). Correct diagnosis and effective
therapy is performed by cooperation of radiologists, oncological and orthopedics surgeons, clinical
oncologists, radiotherapists, rehabilitants, pathologists, nuclear medicine specialists and molecular
biologists. The most important principle in diagnostics and therapy of primary malignant bone tumors is
multidisciplinary work in experienced centers. Improvement of diagnostics, implementation of combined
therapy and technological developments caused the increase of limb-sparing surgery indications and
better long-term results of their treatment.
Onkol. Prak. Klin. 2010; 6, 6: 355–369
Keywords:
bone sarcomasrecommendationsdiagnosticstherapy
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