open access

Vol 22, No 1 (2019)
Clinical vignette
Submitted: 2018-11-03
Accepted: 2018-11-29
Published online: 2019-01-31
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Multiple photopenic vertebrae in the bone scintigraphy of a young man with Gorham disease: CT and MRI correlation

Ramin Sadeghi1, Sara Shakeri1, Toktam Massoudi1, Fatemeh Farahmandfar1, Farnaz Nesari Javan1
DOI: 10.5603/NMR.2019.0008
·
Pubmed: 31482543
·
Nucl. Med. Rev 2019;22(1):40-42.
Affiliations
  1. Nuclear Medicine Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran, Islamic Republic Of

open access

Vol 22, No 1 (2019)
Clinical vignette
Submitted: 2018-11-03
Accepted: 2018-11-29
Published online: 2019-01-31

Abstract

We report a rare pattern of extensive bone abnormalities on the Tc-99m MDP bone scintigraphy in a patient with Gorham disease. This rare condition is the result of vascular and lymphatic channel proliferation in bony structures which induce bone resorption. Our case is a 28-year-old man with a history of biopsy-proven soft tissue hemangioma in the left thigh, encountered with a recent diagnosis of multiple vertebral hemangiomata in the axial skeleton and progressive bony destructions in the pelvis on CT and MRI images, referred for bone scintigraphy. Multiple photopenic hemangiomata were noted on bone scan.

Abstract

We report a rare pattern of extensive bone abnormalities on the Tc-99m MDP bone scintigraphy in a patient with Gorham disease. This rare condition is the result of vascular and lymphatic channel proliferation in bony structures which induce bone resorption. Our case is a 28-year-old man with a history of biopsy-proven soft tissue hemangioma in the left thigh, encountered with a recent diagnosis of multiple vertebral hemangiomata in the axial skeleton and progressive bony destructions in the pelvis on CT and MRI images, referred for bone scintigraphy. Multiple photopenic hemangiomata were noted on bone scan.

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Keywords

Gorham disease; Bone resorption; Vascular proliferation; Hemangioma

About this article
Title

Multiple photopenic vertebrae in the bone scintigraphy of a young man with Gorham disease: CT and MRI correlation

Journal

Nuclear Medicine Review

Issue

Vol 22, No 1 (2019)

Article type

Clinical vignette

Pages

40-42

Published online

2019-01-31

Page views

725

Article views/downloads

731

DOI

10.5603/NMR.2019.0008

Pubmed

31482543

Bibliographic record

Nucl. Med. Rev 2019;22(1):40-42.

Keywords

Gorham disease
Bone resorption
Vascular proliferation
Hemangioma

Authors

Ramin Sadeghi
Sara Shakeri
Toktam Massoudi
Fatemeh Farahmandfar
Farnaz Nesari Javan

References (11)
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  7. Posadas MD, Viejo Stuart S, Romano O, et al. Gorham-Stout syndrome: a case report. Eur Rev Med Pharmacol Sci. 2014; 18(1 Suppl): 81–83.
  8. Yang RH, Chen PCH, Chang CP, et al. Gorham's disease: the disappearing bone. Clin Nucl Med. 2013; 38(5): 361–364.
  9. Brown RD, Studentsova Y, Margouleff D. Vanishing bone disease of the pelvis. Clin Nucl Med. 2004; 29(11): 709–711.
  10. Park SB, Choi JY, Kim SJ. Gorham-Stout Disease Affecting the Mandible: Bone Scintigraphy and Computed Tomography Findings. Clin Nucl Med. 2017; 42(10): 779–781.
  11. Mabille L, Berenger N, Laredo JD, et al. Vanishing vertebra. Clin Nucl Med. 1997; 22(1): 49–51.

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