open access

Vol 5, No 2 (2002)
Reviews
Published online: 2002-06-07
Submitted: 2012-01-23
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Evaluation of nuclear medicine tests for the diagnosis of breast carcinoma

Philip C. Grammaticos
Nucl. Med. Rev 2002;5(2):165-170.

open access

Vol 5, No 2 (2002)
Reviews
Published online: 2002-06-07
Submitted: 2012-01-23

Abstract

In this paper, we evaluate nuclear medicine tests used for the diagnosis of breast carcinoma. Breast carcinoma is the most common carcinoma in women in Europe and its early diagnosis and treatment is important for the overall survival of the patients. Scintimammography technique, indications, contraindications and diagnostic procedures for the identification of the sentinel node and the axillary nodes infiltrated by tumour are described. Also, the use of the radiopharmaceuticals, radioactive thallium chloride-201, methylene diphosphonate labelled with technetium-99m, somatostatin receptors labelled with indium-111, diagnostic procedures with the PET camera, the labelled antibodies to CEA with technetium-99m and also the importance of the MRI and the US techniques are mentioned. These tests have greater diagnostic accuracy as compared to X-ray mammography, clinical examination, MRI and the US technique. Tumour markers in vitro are recommended for the follow- up of metastatic breast carcinoma.

Abstract

In this paper, we evaluate nuclear medicine tests used for the diagnosis of breast carcinoma. Breast carcinoma is the most common carcinoma in women in Europe and its early diagnosis and treatment is important for the overall survival of the patients. Scintimammography technique, indications, contraindications and diagnostic procedures for the identification of the sentinel node and the axillary nodes infiltrated by tumour are described. Also, the use of the radiopharmaceuticals, radioactive thallium chloride-201, methylene diphosphonate labelled with technetium-99m, somatostatin receptors labelled with indium-111, diagnostic procedures with the PET camera, the labelled antibodies to CEA with technetium-99m and also the importance of the MRI and the US techniques are mentioned. These tests have greater diagnostic accuracy as compared to X-ray mammography, clinical examination, MRI and the US technique. Tumour markers in vitro are recommended for the follow- up of metastatic breast carcinoma.
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Keywords

breast carcinoma; scintimammography; lymphoscintigraphy; 99mTc-sestamibi; 99mTc-tetrophosmin

About this article
Title

Evaluation of nuclear medicine tests for the diagnosis of breast carcinoma

Journal

Nuclear Medicine Review

Issue

Vol 5, No 2 (2002)

Pages

165-170

Published online

2002-06-07

Bibliographic record

Nucl. Med. Rev 2002;5(2):165-170.

Keywords

breast carcinoma
scintimammography
lymphoscintigraphy
99mTc-sestamibi
99mTc-tetrophosmin

Authors

Philip C. Grammaticos

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