Vol 5, No 2 (2002)
Review paper
Submitted: 2012-01-23
Published online: 2002-06-07
Evaluation of nuclear medicine tests for the diagnosis of breast carcinoma
Philip C. Grammaticos
Nucl. Med. Rev 2002;5(2):165-170.
Vol 5, No 2 (2002)
Reviews
Submitted: 2012-01-23
Published online: 2002-06-07
Abstract
In this paper, we evaluate nuclear medicine tests used for the diagnosis of breast carcinoma. Breast carcinoma is the most common carcinoma in women in Europe and its early diagnosis and treatment is important for the overall survival of the patients. Scintimammography technique, indications, contraindications and diagnostic procedures for the identification of the
sentinel node and the axillary nodes infiltrated by tumour are described. Also, the use of the radiopharmaceuticals, radioactive thallium chloride-201, methylene diphosphonate labelled with technetium-99m, somatostatin receptors labelled with indium-111, diagnostic procedures with the PET camera, the labelled antibodies to CEA with technetium-99m and also the importance of the MRI and the US techniques are mentioned. These tests have greater diagnostic accuracy as compared to X-ray mammography, clinical examination, MRI and the US technique. Tumour markers in vitro are recommended for the follow-
up of metastatic breast carcinoma.
Abstract
In this paper, we evaluate nuclear medicine tests used for the diagnosis of breast carcinoma. Breast carcinoma is the most common carcinoma in women in Europe and its early diagnosis and treatment is important for the overall survival of the patients. Scintimammography technique, indications, contraindications and diagnostic procedures for the identification of the
sentinel node and the axillary nodes infiltrated by tumour are described. Also, the use of the radiopharmaceuticals, radioactive thallium chloride-201, methylene diphosphonate labelled with technetium-99m, somatostatin receptors labelled with indium-111, diagnostic procedures with the PET camera, the labelled antibodies to CEA with technetium-99m and also the importance of the MRI and the US techniques are mentioned. These tests have greater diagnostic accuracy as compared to X-ray mammography, clinical examination, MRI and the US technique. Tumour markers in vitro are recommended for the follow-
up of metastatic breast carcinoma.
Keywords
breast carcinoma; scintimammography; lymphoscintigraphy; 99mTc-sestamibi; 99mTc-tetrophosmin
Title
Evaluation of nuclear medicine tests for the diagnosis of breast carcinoma
Journal
Nuclear Medicine Review
Issue
Vol 5, No 2 (2002)
Article type
Review paper
Pages
165-170
Published online
2002-06-07
Page views
436
Article views/downloads
1110
Bibliographic record
Nucl. Med. Rev 2002;5(2):165-170.
Keywords
breast carcinoma
scintimammography
lymphoscintigraphy
99mTc-sestamibi
99mTc-tetrophosmin
Authors
Philip C. Grammaticos