Sentinel lymph node detection in canine oncological patients
Abstract
MATERIAL AND METHODS: In this pilot study, 24 client-owned spontaneously tumorous dogs presented for sentinel lymph node detection. A multiple method was used with a nuclear medicine technique (injection of 99mTc human serum albumin colloid) with scintigraphy and intraoperative guidance, and blue dye injection.
RESULTS: Of the 35 lymph nodes histologically demonstrated to contain metastases, 34 (97%) were found by radioguided surgery, which means that one would have been missed in the intraoperative localisation process; 31 nodes (89%) were clearly visualised in the gamma camera images; only 27 (77%) were blue-stained by vital dye; a mere 8 lymph nodes (23%) were enlarged and therefore easily detectable by palpation.
CONCLUSIONS: Data obtained from the harmless application of the sentinel node concept are useful for the radiopharmaceutist. The sentinel lymph node concept is well applicable in the veterinary clinic.
Abstract
MATERIAL AND METHODS: In this pilot study, 24 client-owned spontaneously tumorous dogs presented for sentinel lymph node detection. A multiple method was used with a nuclear medicine technique (injection of 99mTc human serum albumin colloid) with scintigraphy and intraoperative guidance, and blue dye injection.
RESULTS: Of the 35 lymph nodes histologically demonstrated to contain metastases, 34 (97%) were found by radioguided surgery, which means that one would have been missed in the intraoperative localisation process; 31 nodes (89%) were clearly visualised in the gamma camera images; only 27 (77%) were blue-stained by vital dye; a mere 8 lymph nodes (23%) were enlarged and therefore easily detectable by palpation.
CONCLUSIONS: Data obtained from the harmless application of the sentinel node concept are useful for the radiopharmaceutist. The sentinel lymph node concept is well applicable in the veterinary clinic.
Keywords
sentinel lymph node detection; 99mTc HSA colloid; naturally occurring canine tumours; spontaneous animal model
About this articleTitle
Sentinel lymph node detection in canine oncological patients
Journal
Issue
Pages
139-144
Published online
2002-06-07
Page views
1042
Bibliographic record
Nucl. Med. Rev 2002;5(2):139-144.
Keywords
sentinel lymph node detection
99mTc HSA colloid
naturally occurring canine tumours
spontaneous animal model
Authors
Lajos Balogh
Julianna Thuroczy
Gábor Andocs
Domokos Mathé
Pradip Chaudhari
Edina Perge
Imre Biksi
András Polyák
Réka Király
Gyōzō A. Jánoki
