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Assessment of clinical usefulness of parametric clearance images in diagnosis of kidney cicatrisation in children with chronic infections of the urinary tract
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Abstract
MATERIAL AND METHODS: Forty-one patients (age 4–19 years), 28 girls and 13 boys, participated in the study. Altogether, 73 kidneys were analyzed (in 9 patients, only one kidney). In each patient dynamic renal scintigraphy was performed after IV administration of 99mTc EC (ethylenedicysteine) and static planar renal scintigraphy using 99mTc-DMSA (dimercaptosuccinic acid) as a reference method. From the dynamic study, summation and parametric clearance images were generated. Each kidney was divided into 3 segments (upper, middle, lower); altogether 219 segments were evaluated by modified Howard’s scale. Planar and oblique projection images were compared with corresponding summation and parametric clearance images.
RESULTS AND CONCLUSIONS: Parametric clearance imaging has a higher sensitivity and accuracy for detection of regional post-inflammatory changes in the kidneys than conventional summation images (p < 0.05) and shows parenchymal changes similarly to static scintigraphy (high Cohen’s kappa index).
Nuclear Med Rev 2010; 13, 1: 8–14
Abstract
MATERIAL AND METHODS: Forty-one patients (age 4–19 years), 28 girls and 13 boys, participated in the study. Altogether, 73 kidneys were analyzed (in 9 patients, only one kidney). In each patient dynamic renal scintigraphy was performed after IV administration of 99mTc EC (ethylenedicysteine) and static planar renal scintigraphy using 99mTc-DMSA (dimercaptosuccinic acid) as a reference method. From the dynamic study, summation and parametric clearance images were generated. Each kidney was divided into 3 segments (upper, middle, lower); altogether 219 segments were evaluated by modified Howard’s scale. Planar and oblique projection images were compared with corresponding summation and parametric clearance images.
RESULTS AND CONCLUSIONS: Parametric clearance imaging has a higher sensitivity and accuracy for detection of regional post-inflammatory changes in the kidneys than conventional summation images (p < 0.05) and shows parenchymal changes similarly to static scintigraphy (high Cohen’s kappa index).
Nuclear Med Rev 2010; 13, 1: 8–14
Keywords
urinary tract infections; renal scars; parametric clearance images
Title
Assessment of clinical usefulness of parametric clearance images in diagnosis of kidney cicatrisation in children with chronic infections of the urinary tract
Journal
Issue
Pages
8-14
Published online
2010-12-01
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493
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1803
Bibliographic record
Nucl. Med. Rev 2010;13(1):8-14.
Keywords
urinary tract infections
renal scars
parametric clearance images
Authors
Ewa Pietrzak-Stelmasial
Izabela Frieske
Małgorzata Bieńkiewicz
Wojciech Woźnicki
Magdalena Kowalewska-Pietrzak
Krystyna Bubińska
Wojciech Młynarski
Anna Płachcińska
Jacek Kuśmierek