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Vol 14, No 2 (2011)
Research paper
Submitted: 2012-01-23
Published online: 2012-01-04
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The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: a case report and review of the literature

Hamid Javadi, Sara Jallalat, Gholamreza Pourbehi, Shahriar Semnani, Mehdi Mogharrabi, Iraj Nabipour, Mohammadreza Ravanbod, Abdullatif Amini, Majid Assadi
Nucl. Med. Rev 2011;14(2):112-115.

open access

Vol 14, No 2 (2011)
Original articles
Submitted: 2012-01-23
Published online: 2012-01-04

Abstract

Acute myocarditis is one of the most challenging diagnoses and treatments in cardiology. The acute viral myocarditis diagnosis is usually based on high suspicion, history taking, and physical examination. Likewise, the use of chest radiography, electrocardiography (ECG), and echocardiography is helpful in making a final diagnosis, but all are non-specific. In addition, in imaging query, magnetic resonance imaging (MRI) depicts some degree of cardiac inflammation in the course of myocarditis. Myocardial perfusion imaging (MPI) has also been shown to be useful in diagnosis, and this noninvasive technique diminishes the need for myocardial biopsy. The current study presents the diagnostic and prognostic role of MPI in a 25-year-old patient The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: a case report and review of the literature Correspondence to: Majid Assadi, M.D. The Persian Gulf Nuclear Medicine Research Centre, Bushehr University of Medical Sciences Bushehr 3631, Iran Tel: 0098-771-2580169, fax: 0098-771-2541828 e-mail: assadipoya@yahoo.com, asadi@bpums.ac.ir with suspected myocarditis. The patient underwent gated-technetium- 99m-lablled, methoxyisobutyl isonitrile, single photon emission computed tomography (Gated 99mTc-MIBI SPECT) that showed nonheterogeneous absorption with remarkable decreased radiotracer uptake in the myocardium in both stress and rest phases. In addition, the gated mode demonstrated decreased wall motion and thickening of the myocardium with a sum motion score (SMS) of 28, a sum thickening score (STS) of 15, and a measured LVEF of 34%. The study concludes that 99mTC-MIBI SPECT imaging is a useful modality in the preparation of supplementary diagnostic and prognostic information in viral myocarditis.
Nuclear Med Rev 2011; 14, 2: 112–115

Abstract

Acute myocarditis is one of the most challenging diagnoses and treatments in cardiology. The acute viral myocarditis diagnosis is usually based on high suspicion, history taking, and physical examination. Likewise, the use of chest radiography, electrocardiography (ECG), and echocardiography is helpful in making a final diagnosis, but all are non-specific. In addition, in imaging query, magnetic resonance imaging (MRI) depicts some degree of cardiac inflammation in the course of myocarditis. Myocardial perfusion imaging (MPI) has also been shown to be useful in diagnosis, and this noninvasive technique diminishes the need for myocardial biopsy. The current study presents the diagnostic and prognostic role of MPI in a 25-year-old patient The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: a case report and review of the literature Correspondence to: Majid Assadi, M.D. The Persian Gulf Nuclear Medicine Research Centre, Bushehr University of Medical Sciences Bushehr 3631, Iran Tel: 0098-771-2580169, fax: 0098-771-2541828 e-mail: assadipoya@yahoo.com, asadi@bpums.ac.ir with suspected myocarditis. The patient underwent gated-technetium- 99m-lablled, methoxyisobutyl isonitrile, single photon emission computed tomography (Gated 99mTc-MIBI SPECT) that showed nonheterogeneous absorption with remarkable decreased radiotracer uptake in the myocardium in both stress and rest phases. In addition, the gated mode demonstrated decreased wall motion and thickening of the myocardium with a sum motion score (SMS) of 28, a sum thickening score (STS) of 15, and a measured LVEF of 34%. The study concludes that 99mTC-MIBI SPECT imaging is a useful modality in the preparation of supplementary diagnostic and prognostic information in viral myocarditis.
Nuclear Med Rev 2011; 14, 2: 112–115

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Keywords

myocarditis; gated myocardial perfusion scintigraphy (GMPS); echocardiography; electrocardiography (ECG)

About this article
Title

The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: a case report and review of the literature

Journal

Nuclear Medicine Review

Issue

Vol 14, No 2 (2011)

Article type

Research paper

Pages

112-115

Published online

2012-01-04

Page views

1529

Article views/downloads

2584

Bibliographic record

Nucl. Med. Rev 2011;14(2):112-115.

Keywords

myocarditis
gated myocardial perfusion scintigraphy (GMPS)
echocardiography
electrocardiography (ECG)

Authors

Hamid Javadi
Sara Jallalat
Gholamreza Pourbehi
Shahriar Semnani
Mehdi Mogharrabi
Iraj Nabipour
Mohammadreza Ravanbod
Abdullatif Amini
Majid Assadi

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