open access

Vol 71, No 4 (2021)
Research paper (original)
Published online: 2021-08-18
Get Citation

Chronic obstructive pulmonary disease assessment test predicts postoperative complications in patients with lung cancer qualified for lobectomy

Stefan Wesołowski, Tadeusz Orłowski, Paweł Bujnowski
DOI: 10.5603/NJO.2021.0041
·
Nowotwory. Journal of Oncology 2021;71(4):220-224.

open access

Vol 71, No 4 (2021)
Original article
Published online: 2021-08-18

Abstract

Introduction. Patients considered for radical surgery for lung cancer need a functional evaluation to identify those at increased risk of postoperative complications.

Material and methods. We performed an analysis of clinical data of 1214 patients who underwent a single lobectomy for lung cancer. To assess the risk of complications, we used the chronic obstructive pulmonary disease assessment test (CAT).

Results. 254 pulmonary and 51 cardiovascular complications occurred in 216 (17.8%) patients. In 204 patients with a CAT score ≥12 complications occurred more often than in patients with a lower score (26.5% vs. 16.0%; p < 0.001).

Conclusions. In patients undergoing lobectomy for lung cancer, pulmonary complications occurred much more frequently than cardiovascular complications. Patients with a CAT score ≥12 had a higher rate of postoperative complications as compared to those with a lower score.

Abstract

Introduction. Patients considered for radical surgery for lung cancer need a functional evaluation to identify those at increased risk of postoperative complications.

Material and methods. We performed an analysis of clinical data of 1214 patients who underwent a single lobectomy for lung cancer. To assess the risk of complications, we used the chronic obstructive pulmonary disease assessment test (CAT).

Results. 254 pulmonary and 51 cardiovascular complications occurred in 216 (17.8%) patients. In 204 patients with a CAT score ≥12 complications occurred more often than in patients with a lower score (26.5% vs. 16.0%; p < 0.001).

Conclusions. In patients undergoing lobectomy for lung cancer, pulmonary complications occurred much more frequently than cardiovascular complications. Patients with a CAT score ≥12 had a higher rate of postoperative complications as compared to those with a lower score.

Get Citation

Keywords

lung cancer; lung resection; preoperative evaluation; CAT

About this article
Title

Chronic obstructive pulmonary disease assessment test predicts postoperative complications in patients with lung cancer qualified for lobectomy

Journal

Nowotwory. Journal of Oncology

Issue

Vol 71, No 4 (2021)

Article type

Research paper (original)

Pages

220-224

Published online

2021-08-18

DOI

10.5603/NJO.2021.0041

Bibliographic record

Nowotwory. Journal of Oncology 2021;71(4):220-224.

Keywords

lung cancer
lung resection
preoperative evaluation
CAT

Authors

Stefan Wesołowski
Tadeusz Orłowski
Paweł Bujnowski

References (19)
  1. López-Encuentra A. Comorbidity in operable lung cancer. Lung Cancer. 2002; 35(3): 263–269.
  2. Birim O, Kappetein AP, Bogers AdJ. Charlson comorbidity index as a predictor of long-term outcome after surgery for nonsmall cell lung cancer. Eur J Cardiothorac Surg. 2005; 28(5): 759–762.
  3. Lüchtenborg M, Jakobsen E, Krasnik M, et al. The effect of comorbidity on stage-specific survival in resected non-small cell lung cancer patients. Eur J Cancer. 2012; 48(18): 3386–3395.
  4. Ambrogi V, Pompeo E, Elia S, et al. The impact of cardiovascular comorbidity on the outcome of surgery for stage I and II non-small-cell lung cancer1. Eur J Cardiothorac Surg. 2003; 23(5): 811–817.
  5. Brunelli A, Charloux A, Bolliger CT, et al. European Respiratory Society and European Society of Thoracic Surgeons joint task force on fitness for radical therapy. ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy). Eur Respir J. 2009; 34(1): 17–41.
  6. Brunelli A, Kim AW, Berger KI, et al. Physiologic evaluation of the patient with lung cancer being considered for resectional surgery: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013; 143(5 Suppl): e166S–e190S.
  7. Brunelli A, Varela G, Salati M, et al. Recalibration of the revised cardiac risk index in lung resection candidates. Ann Thorac Surg. 2010; 90(1): 199–203.
  8. Jones PW, Harding G, Berry P, et al. Development and first validation of the COPD Assessment Test. Eur Respir J. 2009; 34(3): 648–654.
  9. Quanjer PH, Stanojevic S, Cole TJ, et al. ERS Global Lung Function Initiative. Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J. 2012; 40(6): 1324–1343.
  10. Cotes JE, Chinn DJ, Quanjer PH, et al. Standardization of the measurement of transfer factor (diffusing capacity). Report Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J Suppl. 1993; 16: 41–52.
  11. Global Initiative for Chronic Obstructive Lung Disease (GOLD)[internet]. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. 2019. https://goldcopd.org/gold-reports/ (10.04.2020).
  12. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004; 240(2): 205–213.
  13. Ferguson MK, Celauro AD, Vigneswaran WT. Validation of a modified scoring system for cardiovascular risk associated with major lung resection. Eur J Cardiothorac Surg. 2012; 41(3): 598–602.
  14. Jones PW. Health status measurement in chronic obstructive pulmonary disease. Thorax. 2001; 56(11): 880–887.
  15. Agusti A, Calverley PMA, Celli B, et al. Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res. 2010; 11: 122.
  16. Kelly JL, Bamsey O, Smith C, et al. Health status assessment in routine clinical practice: the chronic obstructive pulmonary disease assessment test score in outpatients. Respiration. 2012; 84(3): 193–199.
  17. Raghavan N, Lam YM, Webb KA, et al. Components of the COPD Assessment Test (CAT) associated with a diagnosis of COPD in a random population sample. COPD. 2012; 9(2): 175–183.
  18. Jones PW, Brusselle G, Dal Negro RW, et al. Health-related quality of life in patients by COPD severity within primary care in Europe. Respir Med. 2011; 105(1): 57–66.
  19. Kim ES, Kim YT, Kang CH, et al. Prevalence of and risk factors for postoperative pulmonary complications after lung cancer surgery in patients with early-stage COPD. Int J Chron Obstruct Pulmon Dis. 2016; 11: 1317–1326.

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Wydawcą serwisu jest VM Media sp. z o.o. VM Group sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail: viamedica@viamedica.pl